Phosphodiester Bonds in DNA and RNA

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

What is the role of H1 in DNA packaging in eukaryotes?

  • Stabilizing both nucleosome structure and higher-order chromatin architecture (correct)
  • Linking the histone cores with linker DNA
  • Forming the histone octamer
  • Compressing and folding the 300-nm fiber

During mitosis, what happens to the chromosomes?

  • They wrap around the nucleosome twice
  • They form looped domains
  • They condense even further (correct)
  • They become less condensed to allow for gene expression

How many H2A-H2B dimers and H3-H4 dimers form the histone octamer?

  • Two of each (correct)
  • Four of each
  • One of each
  • Three of each

What is the purpose of the 30-nm chromatin fiber in DNA packaging?

<p>Facilitating gene expression (A)</p> Signup and view all the answers

Which protein is not involved in the formation of the histone octamer?

<p>H1 (B)</p> Signup and view all the answers

What is the function of linker DNA in DNA packaging?

<p>Link the histone cores with H1 protein (B)</p> Signup and view all the answers

In DNA packaging to produce a chromatid of a chromosome, what process follows tight coiling of the 250-nm wide-fiber?

<p>Compressing and folding the 300-nm fiber (C)</p> Signup and view all the answers

What type of nucleotide substitution occurs in mRNA compared to the coding strand?

<p>Adenine is substituted by Uracil (C)</p> Signup and view all the answers

Which components form the spliceosome involved in splicing pre-mRNA?

<p>Proteins and snRNA (A)</p> Signup and view all the answers

What is the function of the branch point nucleotide in the splicing process?

<p>Attacks the 5’ splice site to cut the mRNA (B)</p> Signup and view all the answers

Where is the acceptor site located in the splicing process?

<p>At the 3’ end of an exon (B)</p> Signup and view all the answers

What happens when ribonucleoprotein complexes (snRNPs) bind to exon-intron junctions?

<p>Cutting at splice donor and splice acceptor sites (A)</p> Signup and view all the answers

Which sequences are recognized by spliceosomes during splicing?

<p>GU and AG sequences at intron ends (A)</p> Signup and view all the answers

What is the role of spliceosomes in mRNA splicing?

<p>Intron removal and exon joining (A)</p> Signup and view all the answers

What is the role of Poly(A) polymerase enzyme in mRNA processing?

<p>Adds a poly(A) tail to the 3’ end of the pre-mRNA (B)</p> Signup and view all the answers

At what position downstream of the polyadenylation signal sequence does the endonuclease enzyme cleave the pre-mRNA strand?

<p>~ 10-35 bp (D)</p> Signup and view all the answers

Which enzyme is responsible for cleaving the pre-mRNA strand?

<p>Endonuclease enzyme (B)</p> Signup and view all the answers

What is the function of the poly(A) tail added to mRNA?

<p>Protects mRNA from degradation (D)</p> Signup and view all the answers

In what manner does Poly(A) polymerase add the poly(A) tail to pre-mRNA?

<p>Template-independent (A)</p> Signup and view all the answers

What is the size limit of the poly(A) tail added to pre-mRNA in mammalian cells?

<p>~ 200 nucleotides (D)</p> Signup and view all the answers

Which process described is crucial for tRNA to bind to the correct sequence of mRNA during translation?

<p>Forming hairpin loops (A)</p> Signup and view all the answers

What is the role of the initiator tRNA in translation?

<p>Carrying the Met amino acid to the A-site (C)</p> Signup and view all the answers

What distinguishes the start codon for polypeptide synthesis?

<p>It differentiates initiating methionyl tRNAs from internal methionine tRNAs (A)</p> Signup and view all the answers

Which of the following is NOT a role of the anticodon loop?

<p>Facilitating peptide bond formation at the P-site (B)</p> Signup and view all the answers

Why are base substitutions sometimes not changing an amino acid?

<p>Because of degeneracy in the genetic code (C)</p> Signup and view all the answers

How is the termination of an amino acid chain signaled in translation?

<p>By one of the three nonsense or termination codons (D)</p> Signup and view all the answers

Where does the uncharged tRNA move after peptide bond formation?

<p>To the E-site (B)</p> Signup and view all the answers

Which site on the ribosome does the empty tRNA move to after being released?

<p>E-site (A)</p> Signup and view all the answers

What is the term used to describe the many non-apoptotic ways for severely damaged or stressed animal cells to die?

<p>Necrosis (B)</p> Signup and view all the answers

Which process ensures that damaged or infected cells are eliminated before they can threaten animal health?

<p>Apoptosis (C)</p> Signup and view all the answers

How are the two original portions of each chromosome rearranged during crossing-over?

<p>Swapped (C)</p> Signup and view all the answers

Which type of cell death is associated with loss of ion gradient and tissue damage across the membrane?

<p>Necrosis (C)</p> Signup and view all the answers

What is the primary cause of cell death through necrosis?

<p>Depletion of energy (C)</p> Signup and view all the answers

Which pathway involves an extracellular signal leading to cell death?

<p>Extrinsic pathway (A)</p> Signup and view all the answers

In which way do damaged or infected cells die to prevent a threat to animal health?

<p>Apoptosis (A)</p> Signup and view all the answers

What type of cell death involves an intracellular signal, often from the mitochondria?

<p>Intrinsic pathway (C)</p> Signup and view all the answers

Which type of cell death is known for being a programmed process?

<p>Apoptosis (A)</p> Signup and view all the answers

Flashcards are hidden until you start studying

More Like This

Use Quizgecko on...
Browser
Browser