Podcast
Questions and Answers
Which of the following anomalies refers to the absence or underdevelopment of the nose?
Which of the following anomalies refers to the absence or underdevelopment of the nose?
- Choanal atresia
- Nasal aplasia (correct)
- Cleft nose
- Nasal polyps
Choanal atresia is a condition that affects the structure of the lens.
Choanal atresia is a condition that affects the structure of the lens.
False (B)
What is the primary palate responsible for forming?
What is the primary palate responsible for forming?
Upper lip, philtrum, primary palate
The ________ are outpouchings of the forebrain that develop into the retina and optic nerve.
The ________ are outpouchings of the forebrain that develop into the retina and optic nerve.
At what week does the development of the palate begin?
At what week does the development of the palate begin?
The lens vesicle differentiates into lens epithelium and lens fibers after the 8th week.
The lens vesicle differentiates into lens epithelium and lens fibers after the 8th week.
Match the following parts of the eye with their function or description:
Match the following parts of the eye with their function or description:
The ___________ develops from the fusion of the maxillary prominences.
The ___________ develops from the fusion of the maxillary prominences.
When does the lens reach its adult size?
When does the lens reach its adult size?
The corneal stroma is formed from the ectoderm.
The corneal stroma is formed from the ectoderm.
What begins the development of the choroid?
What begins the development of the choroid?
The iris develops from the anterior portion of the optic cup and forms two layers: the stroma and the ______.
The iris develops from the anterior portion of the optic cup and forms two layers: the stroma and the ______.
At which weeks does the corneal endothelium start to form?
At which weeks does the corneal endothelium start to form?
Match the following eye structures with their associated development timeline:
Match the following eye structures with their associated development timeline:
The sclera develops from the mesenchymal cells migrating around the optic cup.
The sclera develops from the mesenchymal cells migrating around the optic cup.
What are the two layers into which the choroidal mesenchyme differentiates?
What are the two layers into which the choroidal mesenchyme differentiates?
At what week of embryonic development does the cochlear duct complete its 2.5 turns?
At what week of embryonic development does the cochlear duct complete its 2.5 turns?
The organ of Corti is formed from the merging of inner and outer epithelial ridges.
The organ of Corti is formed from the merging of inner and outer epithelial ridges.
What structures arise from the flattened outpouchings of the otic vesicle during embryonic development?
What structures arise from the flattened outpouchings of the otic vesicle during embryonic development?
The ___ gives rise to the eustachian tube during the development of the middle ear.
The ___ gives rise to the eustachian tube during the development of the middle ear.
Match the following anatomical structures with their corresponding development stages or features:
Match the following anatomical structures with their corresponding development stages or features:
Which of the following is NOT considered an anomaly of the inner ear?
Which of the following is NOT considered an anomaly of the inner ear?
The middle ear development begins at the 5th week of embryonic development.
The middle ear development begins at the 5th week of embryonic development.
What are the three types of anomalies that can occur in the cochlea?
What are the three types of anomalies that can occur in the cochlea?
What does the first pharyngeal pouch give rise to?
What does the first pharyngeal pouch give rise to?
The ventral portion of the third pouch becomes the inferior parathyroid gland.
The ventral portion of the third pouch becomes the inferior parathyroid gland.
Which muscle is associated with the second arch?
Which muscle is associated with the second arch?
The dorsal portion of the fourth pouch becomes the __________ gland.
The dorsal portion of the fourth pouch becomes the __________ gland.
Which of the following anomalies is characterized by the premature fusion of skull bones?
Which of the following anomalies is characterized by the premature fusion of skull bones?
Hemifacial Microsomia is also known for underdevelopment of both sides of the face.
Hemifacial Microsomia is also known for underdevelopment of both sides of the face.
Which muscles are derived from the fourth arch?
Which muscles are derived from the fourth arch?
What are the two prominent facial structures affected by Treacher Collins Syndrome?
What are the two prominent facial structures affected by Treacher Collins Syndrome?
What do the second to fourth clefts primarily form during development?
What do the second to fourth clefts primarily form during development?
Match the arch with its corresponding structures or muscles:
Match the arch with its corresponding structures or muscles:
The development of the nose begins with the fusion of the medial nasal prominence to form the ______.
The development of the nose begins with the fusion of the medial nasal prominence to form the ______.
Match the following anomalies with their characteristics:
Match the following anomalies with their characteristics:
The part of the third pharyngeal pouch that becomes the __________ gland is the dorsal portion.
The part of the third pharyngeal pouch that becomes the __________ gland is the dorsal portion.
At what weeks do the cheek prominences begin to form during embryonic development?
At what weeks do the cheek prominences begin to form during embryonic development?
The nasal septum begins to form in the 7th to 8th week of embryonic development.
The nasal septum begins to form in the 7th to 8th week of embryonic development.
During which weeks does the maxillary process contribute to the development of cheek prominences?
During which weeks does the maxillary process contribute to the development of cheek prominences?
What forms in the vitreous space between the lens and retina during the 6th to 7th week of embryonic development?
What forms in the vitreous space between the lens and retina during the 6th to 7th week of embryonic development?
The vitreous body consists of a solid structure that does not provide cushioning to the retina.
The vitreous body consists of a solid structure that does not provide cushioning to the retina.
What is the term for the condition characterized by the absence of one or both eyes?
What is the term for the condition characterized by the absence of one or both eyes?
The _______ forms the saccule and the cochlear duct during inner ear development.
The _______ forms the saccule and the cochlear duct during inner ear development.
Match each eye anomaly with its description:
Match each eye anomaly with its description:
At what week does the eye continue to grow and refine its shape, completing the formation of the iris, pupil, and sclera?
At what week does the eye continue to grow and refine its shape, completing the formation of the iris, pupil, and sclera?
Retinitis pigmentosa is a genetic disorder that affects the outer ear.
Retinitis pigmentosa is a genetic disorder that affects the outer ear.
What condition involves the dislocation of the lens?
What condition involves the dislocation of the lens?
Flashcards
Craniosynostosis
Craniosynostosis
Premature fusion of skull bones, leading to an abnormal head shape.
Cleft Lip and Palate
Cleft Lip and Palate
A congenital condition where the upper lip and/or palate have a gap.
Hemifacial Microsomia
Hemifacial Microsomia
Underdevelopment of one side of the face.
Treacher Collins Syndrome
Treacher Collins Syndrome
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Development of Cheeks
Development of Cheeks
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Development of Nose
Development of Nose
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Formation of Nasal Pits
Formation of Nasal Pits
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Formation of Nasal Cavities
Formation of Nasal Cavities
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What does the second pharyngeal arch develop into?
What does the second pharyngeal arch develop into?
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What structures are formed from the third pharyngeal arch?
What structures are formed from the third pharyngeal arch?
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What muscles develop from the fourth pharyngeal arch?
What muscles develop from the fourth pharyngeal arch?
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What does the sixth pharyngeal arch form?
What does the sixth pharyngeal arch form?
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What structures develop from the first pharyngeal pouch and cleft?
What structures develop from the first pharyngeal pouch and cleft?
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What happens to the second to fourth pharyngeal clefts?
What happens to the second to fourth pharyngeal clefts?
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What structures arise from the dorsal and ventral portions of the third pharyngeal pouch?
What structures arise from the dorsal and ventral portions of the third pharyngeal pouch?
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What do the dorsal and ventral portions of the fourth pharyngeal pouch develop into?
What do the dorsal and ventral portions of the fourth pharyngeal pouch develop into?
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Nasal Development (Week 12 onwards)
Nasal Development (Week 12 onwards)
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Cleft Nose
Cleft Nose
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Nasal Aplasia
Nasal Aplasia
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Nasal Proboscis
Nasal Proboscis
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Choanal Atresia
Choanal Atresia
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Nasal Septal Deviation
Nasal Septal Deviation
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Nasal Polyps
Nasal Polyps
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Primary Palate Development
Primary Palate Development
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Vitreous Humor
Vitreous Humor
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Vitreous Fibers
Vitreous Fibers
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Microphthalmia
Microphthalmia
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Anophthalmia
Anophthalmia
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Coloboma
Coloboma
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Ptosis
Ptosis
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Keratoconus
Keratoconus
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Retinitis Pigmentosa
Retinitis Pigmentosa
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What is the cornea?
What is the cornea?
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How does the cornea develop?
How does the cornea develop?
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What is the choroid?
What is the choroid?
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How does the choroid develop?
How does the choroid develop?
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What is the sclera?
What is the sclera?
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How does the sclera develop?
How does the sclera develop?
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What is the iris?
What is the iris?
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How is the iris structured?
How is the iris structured?
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Cochlear Duct Development
Cochlear Duct Development
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Organ of Corti Development
Organ of Corti Development
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Semicircular Canal Development
Semicircular Canal Development
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Middle Ear Development (Early Stage)
Middle Ear Development (Early Stage)
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Middle Ear Development (Pharyngeal Pouch)
Middle Ear Development (Pharyngeal Pouch)
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Middle Ear Development (Differentiation)
Middle Ear Development (Differentiation)
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Ossicle Development
Ossicle Development
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Inner Ear Anomalies
Inner Ear Anomalies
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Study Notes
Pharyngeal Apparatus Development
- Pharyngeal apparatus development begins during the 4th-6th week of embryonic development.
- Six pharyngeal arches form in a craniocaudal arrangement.
- Four pharyngeal clefts externally cover each arch.
- Four pharyngeal pouches internally line each arch.
- Each arch is innervated by a cranial nerve:
- First arch: mandibular branch of trigeminal nerve (CN V3)
- Second arch: facial nerve (CN VII)
- Third arch: glossopharyngeal nerve (CN IX)
- Fourth arch: superior laryngeal branch of vagus nerve (CN X)
- Sixth arch: recurrent laryngeal branch of vagus nerve (CN X)
- Muscles and bones originate from pharyngeal arches by the 6th-8th week.
Arch-Specific Structures
ARCH | BONES | MUSCLES |
---|---|---|
FIRST | Mandible, Maxilla, Zygomatic, Temporal, Incus, Malleus | Chewing muscles (Temporalis, Masseter, Pterygoids); Swallowing muscles (Tensor veli palatini, Mylohyoid, Anterior belly of Digastric) |
SECOND | Lesser horns, upper hyoid, Styloid process, Stapes | Stylohyoid, Posterior belly of Digastric, Stapedius, Stylopharyngeus |
THIRD | Rest of hyoid | Levator palatini, Pharyngeal constrictors, Cricothyroid |
FOURTH | ||
SIXTH | Intrinsic muscles of larynx |
Pharyngeal Pouches and Clefts
- The 1st pharyngeal pouch and cleft contribute to middle ear formation.
- The 1st pouch forms the internal auditory meatus (part of the middle ear).
- The 1st cleft develops into the external auditory meatus (ear canal).
- The 2nd-4th pouches and clefts contribute to the formation of tonsils and glands.
Pharyngeal Apparatus Anomalies
- Pierre Robin sequence: underdevelopment of mandible and tongue
- Treacher Collins syndrome: underdevelopment of zygomatic bone and mandible
- Hemifacial microsomia: underdevelopment of mandible and surrounding tissues
- Branchial cleft cysts/fistulas: abnormal development of 2nd pharyngeal cleft
- Thymic hypoplasia: underdevelopment of thymus (3rd pouch)
- Parathyroid gland abnormalities: abnormal development of the parathyroid glands (3rd & 4th pouches)
Face Development
- Facial development begins during the 4th-5th week of embryonic development from facial prominences.
- Frontonasal prominence, maxillary prominences, and mandibular prominences.
- These prominences merge to form the upper lip, nose, and jaw by the 11th-12th week.
Face Anomalies
- Cleft lip/palate: incomplete fusion of facial prominences
- Craniosynostosis: premature fusion of skull bones
- Hemifacial microsomia: underdevelopment of one side of the face
- Treacher Collins syndrome: underdevelopment of facial bones.
Cheeks Development
- Cheeks develop from the 1st & 2nd pharyngeal arches, primarily from the maxillary process, which forms a growth from the 1st arch.
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