Podcast
Questions and Answers
What is a possible reason for pitting on the surface of a tablet?
What is a possible reason for pitting on the surface of a tablet?
- Incorrect die shape and size
- Insufficient lubricant in the granules (correct)
- Poor binding properties of the excipient
- High pressure during compression
What is a characteristic of a rotary tablet machine?
What is a characteristic of a rotary tablet machine?
- It has a high output of 10,000 tablets/min (correct)
- It is composed of multiple sets of punches housed in a square die
- It is used for small scale production
- It is composed of a single set of punches and a die
Why are special excipients required in certain tablet formulations?
Why are special excipients required in certain tablet formulations?
- To improve the color of the tablet
- Because colorants are not uniformly distributed (correct)
- To increase the hardness of the tablet
- To enhance the bioavailability of the active ingredient
What is a characteristic of a single punch tablet machine?
What is a characteristic of a single punch tablet machine?
What is a problem that can occur during tablet manufacture due to insufficient lubricant in the granules?
What is a problem that can occur during tablet manufacture due to insufficient lubricant in the granules?
What is the purpose of the friability test in tablet quality control?
What is the purpose of the friability test in tablet quality control?
What is one of the defects that can be present in a tablet?
What is one of the defects that can be present in a tablet?
What is the advantage of tablets that allows them to mask the unpleasant taste of drugs?
What is the advantage of tablets that allows them to mask the unpleasant taste of drugs?
What is a requirement for an ideal tablet in terms of its size?
What is a requirement for an ideal tablet in terms of its size?
What is a challenge in formulating and manufacturing tablets for certain drugs?
What is a challenge in formulating and manufacturing tablets for certain drugs?
Why may some drugs require encapsulation or entrapment prior to compression?
Why may some drugs require encapsulation or entrapment prior to compression?
What is a major disadvantage of using the slugging process for tablet production?
What is a major disadvantage of using the slugging process for tablet production?
Why is the direct compression method not suitable for high-dose drug formulations?
Why is the direct compression method not suitable for high-dose drug formulations?
What is a potential tablet defect resulting from the direct compression method?
What is a potential tablet defect resulting from the direct compression method?
What is a critical property of an ideal direct compression vehicle?
What is a critical property of an ideal direct compression vehicle?
What is a disadvantage of using the direct compression method for low-dose drug formulations?
What is a disadvantage of using the direct compression method for low-dose drug formulations?
What is an advantage of using the slugging process for tablet production?
What is an advantage of using the slugging process for tablet production?
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