5 Questions
Size reduction involves the production of larger mass units from smaller mass units of the same material.
False
Increasing the energy of impact in size reduction leads to larger particles becoming smaller in size and more numerous.
True
Size reduction has no impact on rates of dissolution, chemical reaction, mixing, extraction, drying, and absorption in pharmacy.
False
According to the text, the size of the finer particles is not related to the internal structure of the material.
False
The production of fine particles through size reduction only impacts oral administration, not topical or parenteral administration.
False
Study Notes
Size Reduction
- Size reduction involves producing smaller mass units from larger mass units of the same material.
Importance of Size Reduction in Pharmacy
- Size reduction enhances rates of: • dissolution • chemical reaction • mixing • extraction • drying • absorption
- This enhancement occurs in: • oral administration • topical application • parenteral administration
Theory of Size Reduction
- When a single particle is subjected to sudden impact and fractured, it yields: • few relatively large particles • a number of fine particles • relatively few particles of intermediate size
- If the energy of the impact is increased: • larger particles become smaller and more numerous • the number of fine particles increases appreciably, but their size does not change greatly
- The size of finer particles relates to the internal structure of the material
- The size of larger particles relates to the energy of impact
Test your knowledge of size reduction in pharmacy with this quiz. Explore the importance of fine particles and their impact on dissolution, chemical reaction, mixing, extraction, drying, and absorption. Perfect for pharmacy students and professionals looking to enhance their understanding of size reduction principles.
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