26 Questions
What is the recommended storage condition for antineoplastic HDs?
In a dedicated refrigerator with negative pressure
According to USP guidelines, what type of HDs can be stored together with non-antineoplastic HDs?
Group 2 HDs
What is the primary purpose of a Closed-System Transfer Device (CSTD) in handling HDs?
To prevent spills and exposures during HD handling
What is required for sterile compounding of HDs?
An externally-ventilated, negative-pressure room
According to USP Chapter, what is the primary focus of the guidelines for handling hazardous drugs?
To ensure safety of the patient, worker, and environment
What type of room is recommended for HD receipt and unpacking?
A negative-pressure room
What is the minimum air exchange rate recommended for HD storage areas?
12 ACPH
Which of the following is a characteristic of a hazardous drug, according to NIOSH?
It exhibits reproductive toxicity
What is the purpose of a Containment Primary Engineering Control (C-PEC)?
To prevent the release of hazardous drugs into the environment
What is the primary function of a Closed-System Transfer Device (CSTD)?
To prevent the escape of hazardous drug during transfer
What is required for sterile compounding of hazardous drugs?
Both primary and secondary engineering controls are needed
How often should the list of hazardous drugs used in a facility be reviewed?
At least annually
What is the purpose of an Assessment of Risk for hazardous drugs?
To identify alternative containment strategies
What type of hazardous drug requires manipulation, according to USP Chapter?
Any hazardous drug requiring manipulation
What is the purpose of a Biological Safety Cabinet (BSC)?
To provide a sterile environment for compounding
Which of the following is an example of a secondary engineering control?
A Containment Secondary Engineering Control (C-SEC)
Which of the following medications requires a separate storage space?
Fulvestrant pre-filled syringe, an antineoplastic HD
What is the primary purpose of a C-PEC?
To minimize worker and environmental exposure to HDs
What is the purpose of a Closed-System Transfer Device (CSTD)?
To offer additional levels of protection during compounding
What is required when handling HDs?
Wearing PPE, including two pairs of chemotherapy gloves
What is the purpose of deactivation in the cleaning steps?
To render the compound inert or inactive
What is the purpose of an ISO Class 7 buffer room?
To provide a space for compounding HDs
What is the purpose of a C-SEC?
To provide a room in which a C-PEC is placed
What is the purpose of a chemotherapy spill kit?
To manage spills larger than can be handled with a spill kit
What is the purpose of sterile compounding requirements?
To ensure aseptic processing and control of contaminants
What is the purpose of respiratory protection?
To provide protection when attending HD spills larger than can be managed with a spill kit
Identify the medication that requires separate storage space. Learn about proper storage of cyclosporine, trastuzumab, testosterone gel, and fulvestrant pre-filled syringe in a pharmacy setting.
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