Pharmacy Antacids and Drug Interactions

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Questions and Answers

Which vitamins are composed of nicotinamide, thiamine, and riboflavin?

  • Vitamin B complex (correct)
  • Vitamin C
  • Vitamin A
  • Vitamin D

Which vitamin is indicated for the prevention and treatment of scurvy?

  • Vitamin K
  • Vitamin C
  • Vitamin D
  • Vitamin A

Which vitamin is associated with preventing or treating rickets?

  • Vitamin K
  • Vitamin E
  • Vitamin D (correct)
  • Vitamin B12

Which deficiency is associated with the treatment of neuromuscular abnormalities?

<p>Vitamin B deficiency (D)</p> Signup and view all the answers

Which of the following is a first-generation antipsychotic?

<p>Haloperidol (A)</p> Signup and view all the answers

Aminoglycoside induced neuropathy is primarily linked to which vitamin deficiency?

<p>Vitamin B (A)</p> Signup and view all the answers

Which of these options includes only second-generation antipsychotic drugs?

<p>Aripiprazole and Clozapine (C)</p> Signup and view all the answers

Which vitamin is specifically required for the treatment of vitamin K deficiency bleeding?

<p>Vitamin K (B)</p> Signup and view all the answers

Which side effect is commonly associated with first-generation antipsychotics?

<p>Extrapyramidal symptoms (D)</p> Signup and view all the answers

What consequence is primarily linked to folic acid deficiency?

<p>Anemia (D)</p> Signup and view all the answers

Thiamine deficiency is most commonly associated with which health issue?

<p>Beriberi (A)</p> Signup and view all the answers

Which of the following is NOT a contraindication of insulin?

<p>Hypertension (D)</p> Signup and view all the answers

Which of these anti-diabetic agents is classified as a biguanide?

<p>Metformin (C)</p> Signup and view all the answers

What is a common side effect of the first-generation antipsychotic medications?

<p>Drowsiness (A)</p> Signup and view all the answers

Which anti-TB drug is contraindicated for patients with optic neuritis and poor vision?

<p>Ethambutol (B)</p> Signup and view all the answers

What contraindication is linked with Isoniazid?

<p>Hepatic disorders (B)</p> Signup and view all the answers

Which therapeutic class is associated with Vitamin A?

<p>Prevention of xerophthalmia (B)</p> Signup and view all the answers

Which drug is not absorbed when taken with aluminum compound antacids?

<p>Ciprofloxacin (C), Tetracycline (D)</p> Signup and view all the answers

What is a side effect of cholinesterase inhibitors overdose?

<p>Increased bronchial secretions (D)</p> Signup and view all the answers

Pyrazinamide is contraindicated in which of the following conditions?

<p>Jaundice (B)</p> Signup and view all the answers

Which drug is most commonly contraindicated in patients with renal impairment?

<p>Cycloserine (B)</p> Signup and view all the answers

In which condition is aspirin contraindicated?

<p>Peptic ulceration (B), Severe heart failure (C)</p> Signup and view all the answers

Which of the following is an adverse effect of analgesics?

<p>Heart damage (A)</p> Signup and view all the answers

Which anti-TB medication is contraindicated for patients with severe heart attacks?

<p>Streptomycin (D)</p> Signup and view all the answers

Which vitamin is essential for preventing xerophthalmia?

<p>Vitamin A (B)</p> Signup and view all the answers

Which of these local reactions are NOT typically caused by vaccine injections?

<p>Hepatotoxicity (D)</p> Signup and view all the answers

Which of the following conditions can result from overdose of cholinesterase inhibitors?

<p>Excessive salivation (B)</p> Signup and view all the answers

Which can be a contraindication for Cycloserine?

<p>Renal impairment (A)</p> Signup and view all the answers

What is a possible side effect of taking analgesics excessively?

<p>Gastro-intestinal ulceration (D)</p> Signup and view all the answers

What is NOT an adverse effect of cholinesterase inhibitors?

<p>Coughing (D)</p> Signup and view all the answers

Which of the following is NOT a common local reaction following vaccine injection?

<p>Nausea (C)</p> Signup and view all the answers

What is the typical dose of folic acid recommended for pregnant women?

<p>400 mcg daily (B)</p> Signup and view all the answers

Which of the following is a potential side effect of corticosteroid nasal sprays?

<p>Nasal irritation (B)</p> Signup and view all the answers

What is an appropriate action to take if a patient is prescribed corticosteroid spray after nasal surgery?

<p>Instruct them on proper spray technique (A)</p> Signup and view all the answers

Which local reaction may occur at the injection site of a vaccine?

<p>Itching (C)</p> Signup and view all the answers

What is the primary role of folic acid supplementation in pregnant women?

<p>Prevent neural tube defects (C)</p> Signup and view all the answers

What is a common guideline when administering corticosteroid nasal sprays after surgery?

<p>Follow prescribed dosage and timing (C)</p> Signup and view all the answers

Which of the following is a reason to monitor a patient using corticosteroid nasal sprays?

<p>To check for potential infections (C)</p> Signup and view all the answers

Flashcards

Antacids Drug Interaction

Aluminum compounds in antacids can bind to certain drugs in the GI tract, reducing their absorption.

Cholinesterase Inhibitor Overdose

Nausea, diarrhea, increased bronchial secretions, salivation, and sweating.

Aspirin Contraindications

Hemophilia, severe heart failure, peptic ulceration, severe heartburn, and children under 16 years.

Adverse Effects of Analgesics

Haematuria, heart damage, vitiligo, vertigo, and gastrointestinal ulceration.

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Local Reactions to Vaccination

Redness, swelling, and pain at the injection site; lymphadenopathy; fever; and rash.

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Ethambutol Contraindication

Optic neuritis and poor vision.

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Pyrazinamide Contraindication

Jaundice.

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Isoniazid Contraindication

Hepatic disorders.

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Streptomycin Contraindication

Myasthenia gravis.

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Cycloserine Contraindication

Epilepsy and severe anxiety.

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Vitamins - Therapeutic Indications

Vitamin C: Treats scurvy; Vitamin A: Prevents xerophthalmia; Vitamin E: Used for some neuromuscular issues; Vitamin D: Prevents rickets; Vitamin B complex: Contains nicotinamide, thiamine, and riboflavin.

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Antipsychotic Precautions

Side effects, drug interactions, patient history of cardiovascular problems, blood pressure changes, weight changes, risk of seizures, and need to follow-ups.

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Local Injection Reactions

Redness, swelling, and pain at the injection site.

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Folic Acid Dosage in Pregnancy

400 micrograms daily, especially before conception and during the first 12 weeks of pregnancy.

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Corticosteroid Spray - Post Nasal Surgery

Instruct on proper use, advise on side effects, monitor for signs of infection, and educate on adherence.

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First-Generation Antipsychotics

Haloperidol, Chlorpromazine, Fluphenazine, Thioridazine.

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Second-Generation Antipsychotics

Risperidone, Clozapine

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Study Notes

Antacids and Drug Interactions

  • Aluminium compounds in antacids can form insoluble complexes, leading to reduced absorption of certain medications.
  • Key medications affected include:
    • Cloxacillin
    • Amoxicillin
    • Ciprofloxacin
    • Tetracycline
    • Erythromycin

Cholinesterase Inhibitor Overdose Effects

  • Overdosing on cholinesterase inhibitors may result in:
    • Nausea
    • Diarrhea
    • Increased bronchial secretions
    • Increased salivation
    • Excessive sweating

Aspirin Contraindications

  • Aspirin should not be used in:
    • Patients with haemophilia
    • Patients with severe heart failure
    • Patients suffering from peptic ulceration
    • Patients experiencing severe heartburn
    • Children under 16 years of age

Adverse Effects of Analgesics

  • Potential adverse effects include:
    • Haematuria
    • Heart damage
    • Vitiligo
    • Vertigo
    • Gastrointestinal ulceration

Local Reactions to Vaccination

  • Possible local reactions from vaccine injections:
    • Hepatotoxicity
    • Gastrointestinal disturbance
    • Hypotension
    • Vomiting
    • Loss of appetite

Anti-Tuberculosis Drug Contraindications

  • Contraindications for Anti-Tb drugs:
    • Ethambutol: Optic neuritis and poor vision
    • Pyrazinamide: Jaundice
    • Isoniazid: Hepatic disorders
    • Streptomycin: Myasthenia gravis
    • Cycloserine: Epilepsy and severe anxiety

Therapeutic Classes of Essential Drugs

  • Matching vitamins with their therapeutic indications:
    • Vitamin C: Treatment of scurvy
    • Vitamin A: Prevention of xerophthalmia
    • Vitamin E: Indicated for some neuromuscular abnormalities
    • Vitamin D: Prevention and treatment of rickets
    • Vitamin B complex: Composed of nicotinamide, thiamine, and riboflavin

Precautions for Antipsychotics

  • Essential precautions when prescribing antipsychotics include monitoring for:
    • Side effects and drug interactions
    • Patient history of cardiovascular issues
    • Blood pressure and weight changes
    • Risk of seizures
    • Regular follow-ups for efficacy and safety

Local Reactions Following Vaccine Injection

  • Common local reactions include:
    • Redness at injection site
    • Swelling at injection site
    • Pain at injection site
    • Lymphadenopathy
    • Fever
    • Rash

Folic Acid Dosage in Pregnant Women

  • Recommended folic acid dose for pregnant women: 400 micrograms daily
  • Important for preventing neural tube defects over the first trimester
  • Dosage duration typically starts before conception and continues through the first 12 weeks of pregnancy

Corticosteroid Spray Management Post-Nasal Surgery

  • Pharmaceutical personnel should:
    • Instruct patient on proper application technique
    • Advise on potential side effects such as nasal irritation
    • Monitor for signs of infection or complications
    • Educate patient on the importance of adherence to therapy

Antipsychotics Classification

  • First-generation antipsychotics include:
    • Haloperidol
    • Chlorpromazine
    • Fluphenazine
    • Thioridazine
  • Second-generation antipsychotics include:
    • Risperidone
    • Clozapine

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