Pharmacology CAT 2 Special PDF

ST JOSEPH COLLEGE OF HEALTH AND ALLIED SCIENCES BASIC TECHNICIAN CERTIFICATE IN PHARMACEUTICAL SCIENCES (NTA LEVEL 4) CONTINOUS ASSASEMENT- THREE MODULE CODE: PST04211...

ST JOSEPH COLLEGE OF HEALTH AND ALLIED SCIENCES BASIC TECHNICIAN CERTIFICATE IN PHARMACEUTICAL SCIENCES (NTA LEVEL 4) CONTINOUS ASSASEMENT- THREE MODULE CODE: PST04211 MODULE NAME: BASIC PHARMACOLOGY GENERAL INSTRUCTIONS:  Read all instructions carefully.  Write your examination number and NACTE registration number on each page you use.  Attempt all questions. The responses should be written in the spaces provided as instructed on each section.  Cellular phones and unauthorized materials are NOT allowed in the examination room  Each essay question to be answered on not more than 2-3 hand written pages.  No additional answer sheets will be provided  Failure to follow instructions will lead to loss of marks  This paper consists of five (5) sections FOR OFFICIAL USE ONLY ALLOCATED SCORED INITIAL INITIAL SECTION TYPES OF QUESTIONS SIGNATURE SIGNATURE MARKS MARKS OF MARKER OF VERIFIER A MULTIPLE CHOICE 10 B MULTIPLE TRUE/FALSE 10 C MATCHING ITEMS 10  D SHORT ANSWER 40 E ESSAY 30 TOTAL 100 A: MULTIPLE CHOICE QUESTIONS (10 MARKS) SECTION INSTRUCTIONS:  This section consists of ten (10) questions  One (1) mark will be awarded for each correct answer 1. Answer item (i) – (x) by WRITING the letter of the most correct answer in the space provided i. Which of the following medicine belongs to a group of local anesthetics: A. Thiopental B. Bupivacaine C. Halothane D. Ketamine E. Mupirocaine ii. Promethazine is a medicine which belongs to ---------------------- class; A. Antidotes B. Muscle relaxant C. Anesthetics D. Anti-allergic E. Anti-epileptic iii. ------------------ are medicines that are helpful in the prevention of various diseases: A. Vaccines  B. Anti-infective agents C. Immunoglobulins D. Immunosuppressants E. Anti-allergics iv. The aminoglycosides are contraindicated in: A. Patients with GIT disturbance B. People with sickle cell C. Patients with pregnancy D. Patients with HIV/AIDS E. People with mental disturbance v. One of the following is a side effect of local anesthetics: A. Hepatotoxicity B. CNS effects C. Renal impairment D. Hypertension E. GIT disturbance vi. Chlorpheniramine maleate should be avoided in: A. Hypersensitivity B. Muscle spasms C. Hypertension D. Vomiting E. Acute porphyria vii. Amoebiasis drugs should NOT be given to patients:  A. Taking anti-diarrhea drugs B. Taking or who have taken alcohol C. With severe heart attacks D. With liver abscess E. With TB disease viii. The following is a contraindication of Rifampicin: A. Myasthenia gravis B. Optic neuritis C. Persistent nausea D. Jaundice E. Depression ix. Supplementation may be required when taking lipid –lowering drugs, as they interfere with the absorption of: A. Ferrous sulphate B. Folic acid C. Vitamins A, D and K D. Calcium E. Vitamins B and C x. Aluminium compounds antacids can form insoluble complexes, that are not absorbed with the following drugs: A. Cloxacillin B. Amoxicillin C. Ciprofloxacin D. Tetracycline E. Erythromycin SECTION B: MULTIPLE TRUE/FALSE QUESTIONS (10 MARKS) INSTRUCTIONS:  This section consists of four (4) questions with five (5) options each  Write the word “TRUE” and NOT letter ‘T’ for a correct statement and the word “FALSE” NOT letter ‘F’ for incorrect statement in the space provided before each option  All responses should be in CAPITAL letters  Half (½) a mark will be awarded for each correct response  Responses with letters “T” and “F” will not be awarded any mark  There will be a penalty of half (½) of allocated marks for responses with small letters. 2. These are the side effects of over dosage of cholinesterase inhibitors: A. __________ Nausea B. __________ Diarrhea C. __________ Increased bronchial secretions D. __________ Increased salivation E. __________ Excessive sweating 3. Aspirin is contraindicated in the following: A. __________ Patients with haemophilia B. __________ Patients with severe heart failure C. __________ Patients with peptic ulceration D. __________ Patients with severe heart burn E. __________ Children under 16 years 4. These are adverse effects of analgesics:  A. __________ Haematuria B. __________ Heart damage C. __________ Vitiligo D. __________ Vertigo E. __________ Gastro-intestinal ulceration 5. Local reactions that may be caused by vaccines injection are: A. __________ Hepatotoxicity B. __________ Gastro-intestinal disturbance C. __________ Hypotension D. __________ vomiting E. __________ Loss of appetite SECTION C: MATCHING ITEMS QUESTIONS (10MARKS) INSTRUCTIONS:  This section consists of two (2) questions matching with five (5) options each.  Match the items from column B with those in column A by writing the letter of the correct response in the space provided on each option. USE CAPITAL LETTERS  Each correct response is awarded one (1) mark.  Each item from column B is used only once. 6. PART ONE Match the contraindications in column B with the most appropriate Anti-Tb drugs in column A S/No Column A: Answer Column B: 1. Ethambutol A: Severe heart attacks 2. Pyrazinamide B: Epilepsy, severe anxiety 3. Isoniazid and depression  4. Streptomycin C: Renal impairment 5. Cycloserine D: Myasthenia gravis E: Optic neuritis and poor vision F: Jaundice G: Drug – induced liver disease H: Hepatic disorders PART TWO Match the examples of medicines in column B with the most appropriate therapeutic classes of essential drugs in column A COLUMN A ANSWER COLUMN B A. Vitamin C A. Prevention of xerophthalmia B. Vitamin A B. composed of nicotinamide, thiamine and riboflavin C. Vitamin E C. prevention and treatment of scurvy D. Vitamin D D. preventing or treating rickets complex E. Vitamin B E. indicated for some neuromuscular abnormalities F. Aminoglycoside induced neuropathy G. Folic acid deficiency H. treatment of vitamin K deficiency bleeding SECTION D: SHORT ANSWER QUESTIONS (40 MARKS) INSTRUCTIONS:  This section consists of eight (8) questions.  Write your answers in the space provided on each question  Write a readable handwrite; DIRTY WORK IS NOT ALLOWED. 7. List five precautions of antipsychotics? (5marks) ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ _____________________________ 8. List four Anticholinergic side-effects which are common in patients on first antipsychotics (4marks) ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ _____________________________ 9. Give three (3) main side effects of ferrous sulphate (3marks) ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ _____________________________ 10. Mention four Ophthamological preparations groups with one example on each (6marks) ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ _____________________________ 11. List five (5) common side effects of anti-hermorhoid drug (5 marks) ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ _____________________________ 12. Mention six (6) side effects expressed as local reactions following injection of a vaccine (6marks) ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ _____________________________ 13 a) Give the dose, dosage and course of folic acid in pregnant women (1marks) ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ____________________________________________________________ b) What measures will you take as Pharmaceutical personnel when a patient has been prescribed with corticosteroid spray after nasal surgery (4marks) ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ _____________________________ 14. Mention 4 First-generation antipsychotics and two Second-generation drugs (6marks) ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ____________________________ SECTION E: GUIDED ESSAY QUESTIONS (30 MARKS) INSTRUCTIONS:  This section consists of three (3) questions which are supposed to be answered in a narrative way  Write your answer on the empty pages of this question paper; each question should start on a new page.  There will be a penalty of three(3) marks if questions are not answered in essay form 15. Describe the contraindications of insulin and five (5) ant diabetic agents 16. Discuss four Extrapyramidal side effects which are particularly common in patients on first -generation antipsychotics