Pharmacology Quiz on Drug Mechanisms and Properties
32 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the function of Fluorouracil in cancer treatment?

  • Enhance DNA repair mechanisms
  • Inhibit thymidylate synthase (correct)
  • Increase dTMP levels
  • Promote cell growth

    • In a healthy human, what is the typical pH range of blood?

  • 7.38-7.42 (correct)
  • 8.1-8.4
  • 6.8-7.0
  • 7.45-7.50

    • What is the main function of Albumin in human plasma?

  • Promotes cell division
  • Binds to acidic and neutral drugs (correct)
  • Enhances blood clotting
  • Binds to basic drugs

    • Why is Pilocarpine delivered as a prodrug at acidic pH?

    <p>Enhances tear secretion</p> Signup and view all the answers

    Where does the breakdown of proteins, carbohydrates, lipids, and whole organelles occur within a cell?

    <p>Lysosomes</p> Signup and view all the answers

    What is the function of Nexium (Esomeprazole) in treating heartburn?

    <p>Decreasing stomach acid production</p> Signup and view all the answers

    During DNA replication, where are Okazaki fragments formed?

    <p>Lagging strand</p> Signup and view all the answers

    Which molecule is known for donating H+ ions to solutions?

    <p>Phosphorus</p> Signup and view all the answers

    What is the main role of Topoisomerase Type I in DNA replication?

    <p>Cleaving one DNA strand and rotating the other</p> Signup and view all the answers

    Which cytoskeletal component do taxanes bind to for their anticancer effects?

    <p>Microtubules</p> Signup and view all the answers

    What is the primary function of histones in regulating gene expression?

    <p>Organizing and compacting DNA</p> Signup and view all the answers

    Which type of solution is composed of a weak acid and its conjugate base that resists pH changes?

    <p>Buffer solution</p> Signup and view all the answers

    How does Fluorouracil exert its anti-cancer effect?

    <p>By inhibiting thymidylate synthase</p> Signup and view all the answers

    What cytoskeletal component does Keratin belong to?

    <p>Intermediate filaments</p> Signup and view all the answers

    Which cellular process regulates the uptake of Low-density Lipoprotein?

    <p>Endocytosis</p> Signup and view all the answers

    What type of genetic mutation results in a change in the amino acid sequence of a protein?

    <p>Missense mutation</p> Signup and view all the answers

    How many amino acids are coded for by an RNA sequence with 2,175 bases, including start and stop codons?

    <p>$725$</p> Signup and view all the answers

    Which enzyme needed for folic acid synthesis do Sulphonamides selectively inhibit in bacteria?

    <p>Dihydropteroate synthetase</p> Signup and view all the answers

    What initiates the breakdown of proteins, carbohydrates, lipids, and organelles within a cell?

    <p>$Lysosomes$</p> Signup and view all the answers

    What causes Adenine and Thymine to be attracted to each other within DNA?

    <p>$Hydrogen$ bonding</p> Signup and view all the answers

    Where does the conversion of the genetic code into an amino acid sequence occur?

    <p>$Translation$</p> Signup and view all the answers

    Which molecule is produced when RNA polymerase transcribes a gene from DNA?

    <p>$mRNA$</p> Signup and view all the answers

    What is the normal ratio of [H2CO3]:[HCO3-] in the blood?

    <p>1:20</p> Signup and view all the answers

    Which cytoskeletal component do taxanes bind to for their anticancer effects?

    <p>Microtubules</p> Signup and view all the answers

    What is the function of Nexium (Esomeprazole) in treating heartburn?

    <p>Inhibits proton pumps</p> Signup and view all the answers

    What is the main role of Topoisomerase Type I in DNA replication?

    <p>Cleaves one DNA strand and rotates the other strand around before resealing the strand</p> Signup and view all the answers

    Which type of solution is composed of a weak acid and its conjugate base that resists pH changes?

    <p>Buffer solution</p> Signup and view all the answers

    Which molecule is known for donating H+ ions to solutions?

    <p>Acids</p> Signup and view all the answers

    What is the first step (initiation) in Translation?

    <p>The ribosome (large and small subunit) assembles around the mRNA molecule.</p> Signup and view all the answers

    What is the binding site and mechanism of action of Streptomycin, an aminoglycoside?

    <p>Binds to the 16S rRNA of the 30S subunit and causes misreading of the genetic code, leading to the production of non-functional proteins.</p> Signup and view all the answers

    What is the function of Topoisomerase Type I in DNA replication?

    <p>Cleaves one DNA strand and rotates the other strand around before resealing the strand</p> Signup and view all the answers

    Which two anti-cancer drugs are topoisomerase inhibitors?

    <p>Topotecan and Irinotecan (Camptosar)</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser