Pharmacology Quiz for Medical Students

Compendium Pharmacologia

• This is a pharmacology compendium, likely a study guide or textbook.
• Tables created by Max Lemke and Ada Ohlsen
• The content covers various topics in pharmacology.

Table of Contents

• The table of contents lists several pharmacology colloquia (likely lectures or seminars) and their corresponding page numbers.
• Topics include drug definitions, direct-acting agonists, mixed action agonists, receptors (alpha, beta, cholinergic), specific diseases (e.g., hypertension, diabetes, pain), and various drug classes (e.g., analgesics, antidepressants, antipsychotics, antifungals, antivirals, antibiotics, etc.).

Pharmacology Colloquium 1

• Definitions:

  • Describes pharmacokinetics (body's reaction to drugs).
  • Describes pharmacodynamics (drugs' effects on the body).
  • Explains first pass effect (pre-systemic metabolism of a drug).
  • Explains metabolism (how drugs are converted to metabolites).
  • Discusses phase 1 and 2 metabolism (oxidation, reduction, hydrolysis, conjugation).

• Zero order elimination: Constant rate of elimination (same amount being lost over time).

• First order elimination: Rate of elimination proportional to amount (same percentage being lost over time).

• Therapeutic Index: Ratio of the toxic dose to the therapeutic dose.

• Agonist: A molecule that binds to a target and activates it.

• Antagonist: A molecule that binds to a target and prevents activation.

• Competitive vs. Non-competitive Antagonist: Competitive are reversible, Non-competitive are irreversible.

Pharmacology Colloquium 2

• Diuretics: Covers different types like Carbonic Anhydrase inhibitors, loop diuretics, thiazides, and potassium-sparing diuretics, their MOA, SE, and indications (e.g., hypertension, heart failure).
• Ca2+ channel blockers: Detailed discussion on mechanism, side effects, indications (e.g., hypertension, angina).
• RAAS inhibitors: Mechanism, side effects, and indications (e.g., hypertension)

Pharmacology Colloquium 3

• Analgesic Pain Ladder: Steps to manage pain, starting with non-opioids (NSAIDs) and progressing to stronger opioids if needed for severe pain.

Pharmacology Colloquium 4

• Lists different anti-seizure drugs, their mechanisms of action, side effects, and indications.

Pharmacology Colloquium 5

• Antifungals: Explores different classes and their mechanism of action, side effects, and indications.
• Antivirals: Explores different classes and their mechanism of action, side effects, and indications, including HIV and Hepatitis.
• Antibiotics: Covers various drug classes of antibiotics, their MOA, SE, and clinical contexts.

Additional Topics

• Direct-Acting Agonists: Specifics on agents like Epinephrine, Norepinephrine, and Dopamine, focusing on their mechanisms, side effects, and clinical uses.

• Mixed Action Agonists: Similar to direct-acting, but includes drugs that both activate receptors and cause release of stored neurotransmitters.

• Alpha Receptors, Beta Receptors: Detail on specific alpha and beta receptors and their associated drugs.

• Cholinergic Agonists and Antagonists: Specifics on cholinergic receptors and the effects of agonist and antagonists

• Antihistamines: Details on H1 and H2 receptor blockers.

• Glucocorticoids and Mineralocorticoids: Details on these steroid hormones and their therapeutic uses.

• Anti-peptic ulcer agents: Describes different types of peptic ulcer agents, their MOA, SE and clinical uses.

• Laxatives: Specifics on different categories and their mechanisms.

• Anti-diarrheal Agents: Details on different drugs, their MOA, SE and clinical uses.

• Gastric Diseases: General info on conditions related to the gastrointestinal tract.

• Additional details from the 11-28 pages cover topics linked to specific diseases, agents, and their mechanisms/uses.