Pharmacology Quiz: Antibiotics and Peptide Synthesis
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Questions and Answers

Cephalosporins are grouped into ____ and are all part of the larger class of antibiotics known as _____.

  • four generations, beta-lactams
  • six generations, macrolides
  • three generations, penicillins
  • five generations, beta-lactams (correct)
  • Fifth-generation cephalosporins are effective against which bacterial strain that other cephalosporins are not?

  • E. coli
  • P. aeruginosa
  • C. difficile
  • S. aureus (correct)
  • Use of high doses of which antibiotic has been associated with biliary sludging?

  • Erythromycin
  • Penicillin
  • Amoxicillin
  • Ceftriaxone (correct)
  • Which antibiotic is the first choice for treating plague and tularemia?

    <p>Tetracycline</p> Signup and view all the answers

    Aminoglycosides are effective against which type of bacteria?

    <p>Gram-negative rods</p> Signup and view all the answers

    Streptomycin resistance develops rapidly through which mechanisms?

    <p>All of the above</p> Signup and view all the answers

    Which antibiotic is used to treat children with enteritis caused by pathogenic strains of E. coli?

    <p>None of the above</p> Signup and view all the answers

    Gentamicin and Tobramycin are effective against all the following bacterial types except?

    <p>Anaerobic bacteria</p> Signup and view all the answers

    Study Notes

    Cephalosporins

    • Cephalosporins are grouped into generations and are part of the larger class of antibiotics known as beta-lactam antibiotics.

    Fifth-Generation Cephalosporins

    • Fifth-generation cephalosporins have activity against S.aureus strains, unlike other cephalosporins.

    Biliary Sludging

    • High doses of certain antibiotics have been associated with biliary sludging.

    Peptide Synthesis

    • Peptide synthesis involves multiple stages, including building and glycosylation.

    Sources of Antibiotics

    • Antibiotics have various sources, including natural and synthetic sources.

    Bacterial Resistance to Antibiotics

    • Bacteria have developed different mechanisms to evade the effects of antibiotics, including enzyme production to degrade antibiotics.

    Mechanisms of Antibiotic Resistance

    • Bacteria can develop resistance to antibiotics through mutations, reducing drug uptake, and producing enzymes to degrade antibiotics.

    Treatment of Infections

    • Tetracyclen is the first choice for treating plague and tularemia infections.

    Aminoglycosides

    • Aminoglycosides are bactericidal against gram-negative bacteria, including E.Coli.

    Streptomycin Resistance

    • Resistance to streptomycin develops rapidly through mutations, reducing drug uptake, and producing enzymes to degrade antibiotics.

    Childhood Infections

    • In children, Neomycin is used to treat intestinal infections caused by pathogenic E.Coll strains.

    Gentamicin and Tobramycin

    • Gentamicin and Tobramycin are used to treat most types of bacterial infections, with some exceptions.

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    Description

    This quiz covers antibiotics, including cephalosporins and their generations, as well as peptide synthesis and its stages. It also touches on the side effects of antibiotics.

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