18 Questions
What is the process by which a drug moves from its administration site into the bloodstream?
Absorption
Which route of administration has 100% bioavailability?
Intravenous (IV)
What occurs when a drug is metabolized in the gut wall and liver before reaching the systemic circulation?
First pass metabolism
What is the circulation of substances from the liver to the bile, followed by entry into the small intestine, and absorption by the enterocyte and transport back to the liver?
Enterohepatic circulation
What is the dispersal of drugs from the systemic circulation to other tissues and the site of action?
Distribution
What is the fraction of the drug that reaches the blood circulation following administration by any route?
Bioavailability
What is the definition of pharmacology?
The study of drugs and their interactions with living systems
What is the primary route of drug administration that involves the digestive tract?
Enteral
What is the process by which a drug is broken down?
Metabolism
Which type of drugs primarily binds to albumin?
Acidic drugs
What is the definition of pharmacokinetics?
The study of the absorption, distribution, metabolism and excretion of drugs
What is the primary function of the Blood Brain Barrier?
To serve as a protective barrier for the brain
What is the structure of the intestinal epithelium composed of?
Two layers of phospholipids with intermingled protein molecules
What is the primary factor that determines the ability of a drug to cross the Blood Brain Barrier?
Lipid solubility
What is the advantage of the enteral route of drug administration?
Effective absorption due to the large surface area of the gastrointestinal tract
What is the only form of the drug available for action, metabolism, and excretion?
The free and unbound fraction of the drug
What is the effect of protein binding on the duration of action of a drug?
It prolongs the duration of action of the drug
Which type of drugs can cross the placental barrier?
Lipid soluble unionized drugs
Test your understanding of pharmacology principles, including drug administration, absorption, distribution, metabolism, and excretion. This quiz covers the basics of pharmacology, ideal for students of pharmacy and medicine.
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