Pharmacology and Pharmacokinetics
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Questions and Answers

A drug that binds to a receptor and prevents a normal body process from occurring is demonstrating which pharmacological principle?

  • Pharmacodynamics (correct)
  • Distribution
  • Pharmacokinetics
  • Absorption

Which pharmacokinetic process involves the movement of a drug from the bloodstream into the tissues of the body?

  • Metabolism
  • Distribution (correct)
  • Elimination
  • Absorption

A patient with impaired liver function may have difficulty with which pharmacokinetic process, potentially requiring dosage adjustments?

  • Absorption
  • Metabolism (correct)
  • Distribution
  • Elimination

Which of the following is NOT a major route of drug elimination from the body?

<p>Saliva (B)</p> Signup and view all the answers

A clinician needs to achieve a rapid onset of drug action for a patient in acute distress. Which route of administration would likely be most appropriate?

<p>Intravenous (D)</p> Signup and view all the answers

If a drug is described as undergoing 'first-pass metabolism,' this primarily affects which pharmacokinetic process after oral administration?

<p>Absorption (D)</p> Signup and view all the answers

A medication is designed to target a specific tissue. Which aspect of pharmacokinetics is most crucial in ensuring the drug reaches the intended site of action?

<p>Extent of distribution (B)</p> Signup and view all the answers

Which scenario exemplifies a pharmacodynamic interaction?

<p>Two drugs bind to the same receptor, producing an additive effect. (B)</p> Signup and view all the answers

Flashcards

Pharmacology

The study of substances interacting with living systems through chemicals.

Pharmacodynamics

Processes describing how drugs affect the body.

Pharmacokinetics

Processes that govern how the body affects drugs.

Absorption

The process by which a drug enters plasma from administration site.

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Distribution

The reversible movement of a drug from bloodstream to tissues.

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Metabolism

Biotransformation of the drug by the liver or tissues.

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Elimination

The removal of the drug and metabolites from the body.

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Route of Administration

Method used to deliver a drug into the body based on therapeutic needs.

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Study Notes

Pharmacology

  • Pharmacology is the study of substances that interact with living systems, often binding to regulatory molecules and influencing normal body processes.
  • Drug-body interactions are categorized into pharmacodynamics (drug's effects on the body) and pharmacokinetics (body's effects on the drug).
  • Pharmacodynamic properties determine the drug class and its suitability for a particular symptom or disease.
  • Pharmacokinetic processes, including absorption, distribution, metabolism, and elimination, are crucial for drug choice and administration, especially for patients with specific health conditions.

Pharmacokinetics

  • Absorption: Drug absorption from the administration site into the bloodstream (plasma).
  • Distribution: The drug can then move from the bloodstream into interstitial and intracellular fluids.
  • Metabolism: Drugs may be modified (metabolized) by the liver or other organs.
  • Elimination: Drugs and their metabolites are removed from the body via urine, bile, or feces.

Drug Administration

  • Drug administration methods are determined by therapeutic objectives (e.g., rapid onset, long-term treatment).
  • Common routes of drug administration include enteral, parenteral, and topical.

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Description

An overview of pharmacology, focusing on how substances interact with biological systems. It also covers pharmacokinetics, detailing drug absorption, distribution, metabolism, and elimination within the body. Understanding these processes is crucial for effective drug administration and treatment strategies.

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