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Pharmacology of Reproductive Tract Infections and STDs

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40 Questions

What is the most common way neonatal infections are acquired?

During passage through an infected cervix or vagina

Which of the following STDs can be transmitted transplacentally?

Syphilis

What is a common complication of STDs in pregnant women?

All of the above

What is the type of organism that causes Bacterial Vaginosis?

Anaerobic bacteria

Which of the following STDs is associated with an increased risk of cancer?

HPV

What is the name of the infection that occurs when an infant is infected with syphilis during pregnancy?

Congenital syphilis

Which gender has a higher incidence of STDs?

Men

What is the name of the infection that occurs when the reproductive organs are damaged?

Pelvic Inflammatory Disease

What is the primary cause of Bacterial Vaginosis?

An imbalance of naturally occurring bacteria in the vagina

What is the recommended treatment for Bacterial Vaginosis in pregnant women?

Metronidazole in all symptomatic pregnant women

What is the primary mechanism of action of Metronidazole?

Disrupting DNA by inhibiting nucleic acid synthesis

What is the primary risk associated with Chlamydia trachomatis infection in women?

All of the above

What is the preferred treatment for Chlamydia trachomatis in pregnancy?

Azithromycin

What is the primary cause of Gonorrhea?

Neisseria gonorrhoeae

What is the recommended treatment for Chlamydia trachomatis in neonates and infants?

Erythromycin and Azithromycin

What is the primary effect of Clindamycin on bacterial infections?

Suppressing protein synthesis

What is the primary method of preventing ophthalmic gonococcal infections in neonates?

Instillation of erythromycin ophthalmic ointment into the newborn's eyes

What is the recommended regimen for treating antimicrobial-resistant N. gonorrhoeae?

Ceftriaxone + Azithromycin

What is the primary symptom of gonococcal infection in men?

Urethral discharge and testicular pain

What is the primary cause of pelvic inflammatory disease (PID)?

Sexually transmitted organisms, especially N. gonorrhoeae

What is the alternative regimen for treating antimicrobial-resistant N. gonorrhoeae if Ceftriaxone is not available?

Cefixime + Azithromycin

What is the consequence of monotherapy with high-dose azithromycin?

Increased risk of resistance

Why is dual therapy recommended for treating antimicrobial-resistant N. gonorrhoeae?

To reduce the risk of resistance

What is the common characteristic of antimicrobial-resistant N. gonorrhoeae?

Resistance to multiple antibiotics

What is the primary goal of empiric treatment in Pelvic Inflammatory Disease (PID)?

To provide broad-spectrum coverage

Which bacterium is known to cause tubal and epithelial destruction?

Bacteroides fragilis

What is the recommended treatment approach for sex partners of individuals with PID?

Screening only for chlamydia and gonorrhea

What is the mechanism of action of cephalosporins?

Inhibition of bacterial cell wall synthesis

What is the primary mode of transmission for Hepatitis A?

Fecal-oral contact or contamination

What is the most common type of genital herpes?

HSV-2

What is the effect of treatment on genital herpes?

Reduces symptoms and decreases transmission

What is a common side effect of antiviral medication for genital herpes?

Nausea and vomiting

What percentage of cervical cancers are caused by HPV 16 and 18?

66%

What is the difference between the bivalent and quadravalent HPV vaccines?

One covers more HPV types than the other

What is the result of untreated congenital syphilis or tertiary syphilis?

Saddle nose deformity

What is the stage of syphilis characterized by a skin rash and mucocutaneous lesions?

Secondary

What is the purpose of the HPV vaccine?

To prevent cervical cancer

What is the percentage of cervical cancer caused by the additional HPV types covered by the 9-valent vaccine?

15%

What is the characteristic of the primary stage of syphilis?

Painless sore

What is the recommendation for sexual partners of individuals with syphilis?

They should be tested and treated

This quiz covers the pharmacology of infectious diseases of the reproductive tract, including sexually transmitted diseases (STDs) and their effects on maternal and infant health during pregnancy. It also discusses the transmission of infections to the fetus and the risks of neonatal infections. Test your knowledge of reproductive health and pharmacology!

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