NSAIDS

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Questions and Answers

What is the primary mechanism of action of acetaminophen?

  • Stimulation of inflammatory responses
  • Inhibition of prostaglandin synthesis
  • Blockage of pain receptors (correct)
  • Inhibition of COX2

Which of the following is NOT a physiological effect of aspirin?

  • Reducing inflammation
  • Reducing fever
  • Stimulation of pain receptors (correct)
  • Inhibition of platelet aggregation

What is the primary mechanism of action of NSAIDs?

  • Inhibition of prostaglandin synthesis (correct)
  • Inhibition of COX2
  • Stimulation of inflammatory responses
  • Inhibition of COX1

What is the chemical class of naproxen?

<p>Propionic acid (A)</p> Signup and view all the answers

What is the mechanism of action of celecoxib?

<p>Inhibition of COX2 (C)</p> Signup and view all the answers

What is the primary cause of inflammatory algesia?

<p>Prostaglandins (C)</p> Signup and view all the answers

What is the drug class of acetaminophen?

<p>Analgesic (B)</p> Signup and view all the answers

What is the primary difference between COX1 and COX2?

<p>COX1 is constitutive, while COX2 is inducible (D)</p> Signup and view all the answers

What is the mechanism of action of ibuprofen and acetaminophen when combined?

<p>Inhibition of prostaglandin synthesis and blockage of pain receptors (B)</p> Signup and view all the answers

What is the primary mechanism of action of aspirin in relation to prostaglandins?

<p>Decrease prostaglandins (A)</p> Signup and view all the answers

Which of the following is a side effect of ibuprofen and acetaminophen combined?

<p>All of the above (D)</p> Signup and view all the answers

What is the chemical class of celecoxib?

<p>COX-2 inhibitor (B)</p> Signup and view all the answers

What is the primary difference between COX1 and COX2 in relation to inflammatory response?

<p>COX2 is involved in inflammatory response, while COX1 is not (A)</p> Signup and view all the answers

What is the primary mechanism of action of NSAIDs?

<p>Inhibiting the production of prostaglandins (C)</p> Signup and view all the answers

What is the primary effect of prostaglandins in the body?

<p>Increasing pain and inflammation (C)</p> Signup and view all the answers

What is the primary difference between aspirin and ibuprofen?

<p>Aspirin is a COX-1 inhibitor, while ibuprofen is a COX-2 inhibitor (D)</p> Signup and view all the answers

What is the primary cause of hyperalgesia?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary mechanism of action of acetaminophen in relation to pain?

<p>Affecting the brain's pain centers (B)</p> Signup and view all the answers

What is the primary mechanism by which NSAIDs, such as ibuprofen and naproxen, reduce pain?

<p>By blocking the production of prostaglandins (D)</p> Signup and view all the answers

What is the primary difference between the physiological effects of aspirin and ibuprofen?

<p>Aspirin only affects COX1, while ibuprofen affects both COX1 and COX2 (C)</p> Signup and view all the answers

What is the primary mechanism by which acetaminophen reduces pain?

<p>By directly stimulating the brain's pain centers (B)</p> Signup and view all the answers

What is the primary effect of prostaglandins in the body?

<p>They cause inflammation and pain (A)</p> Signup and view all the answers

What is the primary mechanism by which celecoxib reduces pain and inflammation?

<p>By selectively inhibiting COX2 (D)</p> Signup and view all the answers

What is the primary difference between the side effects of aspirin and acetaminophen?

<p>Aspirin is more likely to cause stomach ulcers, while acetaminophen is more likely to cause liver damage (B)</p> Signup and view all the answers

What is the primary mechanism by which NSAIDs reduce inflammation?

<p>By blocking the production of prostaglandins (A)</p> Signup and view all the answers

What is the primary difference between the physiological effects of naproxen and celecoxib?

<p>Naproxen is a non-selective inhibitor of COX1 and COX2, while celecoxib is a selective inhibitor of COX2 (D)</p> Signup and view all the answers

What is the primary mechanism by which ibuprofen and acetaminophen combination products reduce pain and inflammation?

<p>By blocking the production of prostaglandins and directly stimulating the brain's pain centers (B)</p> Signup and view all the answers

What is the primary mechanism of action of NSAIDs in reducing pain and inflammation?

<p>Inhibiting COX1 and COX2 enzymes (D)</p> Signup and view all the answers

What is the primary difference between the mechanism of action of acetaminophen and NSAIDs?

<p>Acetaminophen reduces pain by blocking the production of prostaglandins, while NSAIDs reduce inflammation (C)</p> Signup and view all the answers

What is the primary effect of prostaglandins in the body?

<p>They cause pain and inflammation (A)</p> Signup and view all the answers

What is the primary mechanism of action of celecoxib?

<p>It blocks the production of COX2 (D)</p> Signup and view all the answers

What is the primary cause of hyperalgesia?

<p>Inflammation (A)</p> Signup and view all the answers

What is the primary difference between the mechanism of action of aspirin and ibuprofen?

<p>Aspirin reduces pain, while ibuprofen reduces inflammation (D)</p> Signup and view all the answers

What is the primary mechanism of action of ibuprofen and acetaminophen combination products?

<p>They reduce pain and inflammation by blocking prostaglandin production (B)</p> Signup and view all the answers

What is the primary effect of COX1 enzyme?

<p>It produces prostaglandins (B)</p> Signup and view all the answers

What is the primary difference between the side effects of aspirin and ibuprofen?

<p>Aspirin causes stomach ulcers, while ibuprofen causes kidney damage (A)</p> Signup and view all the answers

What is the primary function of prostaglandins in the body?

<p>To increase pain and inflammation (B)</p> Signup and view all the answers

What is the main difference between COX1 and COX2 in terms of their products?

<p>COX1 produces prostaglandins, while COX2 produces prostacyclins (D)</p> Signup and view all the answers

Which of the following NSAIDs is most selective for COX2?

<p>Celecoxib (D)</p> Signup and view all the answers

What is the primary mechanism by which acetaminophen reduces pain?

<p>Inhibiting the production of bradykinin (B)</p> Signup and view all the answers

What is the primary effect of inhibiting COX1?

<p>Reducing platelet aggregation (C)</p> Signup and view all the answers

What is the primary mechanism by which NSAIDs reduce inflammation?

<p>Inhibiting the production of prostaglandins (D)</p> Signup and view all the answers

What is the primary cause of allodynia?

<p>Increased sensitivity of pain receptors (D)</p> Signup and view all the answers

What is the primary difference between the mechanism of action of acetaminophen and NSAIDs?

<p>Acetaminophen inhibits the production of bradykinin, while NSAIDs inhibit the production of prostaglandins (D)</p> Signup and view all the answers

What is the primary mechanism by which ibuprofen and acetaminophen combination products reduce pain and inflammation?

<p>Inhibiting the production of prostaglandins and bradykinin (D)</p> Signup and view all the answers

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