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Questions and Answers
What is the common property of injectable local anesthetic agents?
What is the common property of injectable local anesthetic agents?
Which of the following is a characteristic of an ideal local anesthetic?
Which of the following is a characteristic of an ideal local anesthetic?
How do local anesthetics affect nerve conduction?
How do local anesthetics affect nerve conduction?
What do local anesthetics form when injected into the body?
What do local anesthetics form when injected into the body?
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What is the primary mode of action of local anesthetics according to the most favored theory?
What is the primary mode of action of local anesthetics according to the most favored theory?
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Which type of local anesthetics are commonly used esters, including tetracaine, procaine, and cocaine?
Which type of local anesthetics are commonly used esters, including tetracaine, procaine, and cocaine?
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Which theory of action of local anesthesia suggests that the local anesthetic dissolves in the lipid contents of nerve tissues, leading to temporary coagulation and prevention of nerve impulses conduction?
Which theory of action of local anesthesia suggests that the local anesthetic dissolves in the lipid contents of nerve tissues, leading to temporary coagulation and prevention of nerve impulses conduction?
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Which theory of action of local anesthesia suggests interference with acetylcholine at synaptic function to prevent nerve conduction?
Which theory of action of local anesthesia suggests interference with acetylcholine at synaptic function to prevent nerve conduction?
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What form are local anesthetics dispensed for injection, making them soluble in water & comparatively stable?
What form are local anesthetics dispensed for injection, making them soluble in water & comparatively stable?
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What is responsible for binding to the protein receptor site in sodium channel for nerve conduction blockage?
What is responsible for binding to the protein receptor site in sodium channel for nerve conduction blockage?
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Study Notes
Properties of Local Anesthetic Agents
- Injectable local anesthetic agents have a common property of being amphipathic, meaning they have both hydrophobic and hydrophilic parts.
Ideal Local Anesthetic Characteristics
- An ideal local anesthetic should have a rapid onset, long duration, and low toxicity.
Mechanism of Action
- Local anesthetics affect nerve conduction by blocking the generation and conduction of nerve impulses.
- When injected into the body, local anesthetics form a complex with the sodium channel receptor site.
Types of Local Anesthetics
- Esters, including tetracaine, procaine, and cocaine, are commonly used local anesthetics.
Theories of Action
- The lipid dissolution theory suggests that local anesthetics dissolve in the lipid contents of nerve tissues, leading to temporary coagulation and prevention of nerve impulses conduction.
- The acetylcholine theory suggests that local anesthetics interfere with acetylcholine at synaptic function to prevent nerve conduction.
Dispensing of Local Anesthetics
- Local anesthetics are dispensed for injection in a hydrochloride salt form, making them soluble in water and comparatively stable.
Nerve Conduction Blockage
- The binding of local anesthetics to the protein receptor site in the sodium channel is responsible for nerve conduction blockage.
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Description
Test your knowledge of local anesthetics and their characteristics with this quiz. Topics include local anesthetic agents, ideal characteristics, and more.
