Pharmacology of Gastrointestinal Tract (GIT) - Gastric Secretion and Motility
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Questions and Answers

What is the main function of gastrin in the gastrointestinal tract?

  • Stimulation of vomiting
  • Stimulation of the secretion of acid by parietal cells (correct)
  • Inhibition of acid secretion by parietal cells
  • Regulation of bowel motility and expulsion of feces

    • Which of the following receptors is involved in the stimulation of gastric acid secretion by histamine?

  • H2 receptors (correct)
  • M1 receptors
  • M2 receptors
  • H1 receptors

    • What is the effect of PGE2 and PGI2 on gastric acid secretion?

  • Stimulation of acid secretion
  • Stimulation of vomiting
  • Inhibition of acid secretion (correct)
  • Regulation of bowel motility

    • Which of the following is a gastrin receptor blocker?

    <p>Proglumide</p> Signup and view all the answers

    What is the main action of acetylcholine on parietal cells?

    <p>Stimulation of acid secretion</p> Signup and view all the answers

    What is the term for an ulcer in the part of the digestive tract exposed to gastric secretion?

    <p>Peptic ulcer</p> Signup and view all the answers

    What is a common symptom of peptic ulcer and reflux esophagitis?

    <p>Anorexia</p> Signup and view all the answers

    Which of the following drugs is used to increase the motility of the GIT smooth muscles without causing purgation?

    <p>Domperidone</p> Signup and view all the answers

    What is the main component of the triple therapy used to treat Helicobacter pylori infection?

    <p>PPI, amoxicillin, and clarithromycin</p> Signup and view all the answers

    What is the function of antacids in the treatment of peptic ulcer and reflux esophagitis?

    <p>To neutralize acid</p> Signup and view all the answers

    Which of the following is a type of drug that includes omeprazole, esomeprazole, and lansoprazole?

    <p>Proton pump inhibitors</p> Signup and view all the answers

    What is a complication of peptic ulcer and reflux esophagitis?

    <p>Hemorrhage</p> Signup and view all the answers

    What is the best way to prevent intermittent constipation?

    <p>Having a high fiber diet, adequate fluid intake, regular exercise, and heeding nature's call</p> Signup and view all the answers

    What is the mechanism of action of bulk forming laxatives?

    <p>They absorb water, forming a bulky, emollient gel that distends the colon and promotes peristalsis</p> Signup and view all the answers

    What is the characteristic of osmotic laxatives?

    <p>They are soluble but nonabsorbable compounds</p> Signup and view all the answers

    What is the purpose of using laxatives in addition to relieving constipation?

    <p>To clear the bowel prior to surgery or examinations</p> Signup and view all the answers

    What is the definition of diarrhea?

    <p>The frequent passage of liquid feces</p> Signup and view all the answers

    What is the mechanism of action of fecal (stool) softeners?

    <p>They soften stool material, permitting water and lipids to penetrate</p> Signup and view all the answers

    What is a cause of diarrhea?

    <p>Underlying disease</p> Signup and view all the answers

    When should antidiarrheal agents not be used?

    <p>In patients with bloody diarrhea</p> Signup and view all the answers

    What is the main function of adsorbents in treating diarrhea?

    <p>To absorb bacteria, toxins, and fluid</p> Signup and view all the answers

    What is a valuable physiological response to the ingestion of a toxic substance?

    <p>Vomiting</p> Signup and view all the answers

    Which type of drug is used to treat motion sickness?

    <p>Muscarinic antagonist</p> Signup and view all the answers

    What is the name of the anticholinergic drug used to treat motion sickness?

    <p>Hyoscine</p> Signup and view all the answers

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