Pharmacology of Gastrointestinal Tract (GIT) - Gastric Secretion and Motility

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Questions and Answers

What is the main function of gastrin in the gastrointestinal tract?

Stimulation of vomiting
Stimulation of the secretion of acid by parietal cells (correct)
Inhibition of acid secretion by parietal cells
Regulation of bowel motility and expulsion of feces

Which of the following receptors is involved in the stimulation of gastric acid secretion by histamine?

H2 receptors (correct)
M1 receptors
M2 receptors
H1 receptors

What is the effect of PGE2 and PGI2 on gastric acid secretion?

Stimulation of acid secretion
Stimulation of vomiting
Inhibition of acid secretion (correct)
Regulation of bowel motility

Which of the following is a gastrin receptor blocker?

Proglumide (D) Signup and view all the answers

What is the main action of acetylcholine on parietal cells?

Stimulation of acid secretion (B) Signup and view all the answers

What is the term for an ulcer in the part of the digestive tract exposed to gastric secretion?

Peptic ulcer (B) Signup and view all the answers

What is a common symptom of peptic ulcer and reflux esophagitis?

Anorexia (A) Signup and view all the answers

Which of the following drugs is used to increase the motility of the GIT smooth muscles without causing purgation?

Domperidone (C) Signup and view all the answers

What is the main component of the triple therapy used to treat Helicobacter pylori infection?

PPI, amoxicillin, and clarithromycin (B) Signup and view all the answers

What is the function of antacids in the treatment of peptic ulcer and reflux esophagitis?

To neutralize acid (C) Signup and view all the answers

Which of the following is a type of drug that includes omeprazole, esomeprazole, and lansoprazole?

Proton pump inhibitors (D) Signup and view all the answers

What is a complication of peptic ulcer and reflux esophagitis?

Hemorrhage (C) Signup and view all the answers

What is the best way to prevent intermittent constipation?

Having a high fiber diet, adequate fluid intake, regular exercise, and heeding nature's call (D) Signup and view all the answers

What is the mechanism of action of bulk forming laxatives?

They absorb water, forming a bulky, emollient gel that distends the colon and promotes peristalsis (D) Signup and view all the answers

What is the characteristic of osmotic laxatives?

They are soluble but nonabsorbable compounds (B) Signup and view all the answers

What is the purpose of using laxatives in addition to relieving constipation?

To clear the bowel prior to surgery or examinations (A) Signup and view all the answers

What is the definition of diarrhea?

The frequent passage of liquid feces (B) Signup and view all the answers

What is the mechanism of action of fecal (stool) softeners?

They soften stool material, permitting water and lipids to penetrate (D) Signup and view all the answers

What is a cause of diarrhea?

Underlying disease (C) Signup and view all the answers

When should antidiarrheal agents not be used?

In patients with bloody diarrhea (B) Signup and view all the answers

What is the main function of adsorbents in treating diarrhea?

To absorb bacteria, toxins, and fluid (A) Signup and view all the answers

What is a valuable physiological response to the ingestion of a toxic substance?

Vomiting (C) Signup and view all the answers

Which type of drug is used to treat motion sickness?

Muscarinic antagonist (D) Signup and view all the answers

What is the name of the anticholinergic drug used to treat motion sickness?

Hyoscine (A) Signup and view all the answers

Flashcards

Gastrin's main function?

Stimulates acid secretion by parietal cells in the stomach.

Histamine receptor for acid secretion?

H2 receptors on parietal cells.