Podcast
Questions and Answers
Which of the following adverse effects is associated with Mirabegron (Myrbetriq) and Vibegron?
Which of the following adverse effects is associated with Mirabegron (Myrbetriq) and Vibegron?
What is the main contraindication for Mirabegron and Vibegron?
What is the main contraindication for Mirabegron and Vibegron?
What is the recommended duration of use for Phenazopyridine?
What is the recommended duration of use for Phenazopyridine?
What is the main adverse effect associated with Phenazopyridine?
What is the main adverse effect associated with Phenazopyridine?
Signup and view all the answers
Which enzyme is involved in the metabolism of Mirabegron and Vibegron, leading to potential drug interactions?
Which enzyme is involved in the metabolism of Mirabegron and Vibegron, leading to potential drug interactions?
Signup and view all the answers
Which class of drugs competitively inhibits parietal cells (H2) receptors to inhibit basal & meal stimulated acid secretion?
Which class of drugs competitively inhibits parietal cells (H2) receptors to inhibit basal & meal stimulated acid secretion?
Signup and view all the answers
Which drug class blocks the final common pathway in acid secretion by inhibiting the proton pump?
Which drug class blocks the final common pathway in acid secretion by inhibiting the proton pump?
Signup and view all the answers
Which drug is a central serotonin 5HT3 antagonist in the vomiting center and trigger zone?
Which drug is a central serotonin 5HT3 antagonist in the vomiting center and trigger zone?
Signup and view all the answers
Which drug is a THC derivative and a schedule III drug used as an appetite stimulator and may be used in chemo nausea?
Which drug is a THC derivative and a schedule III drug used as an appetite stimulator and may be used in chemo nausea?
Signup and view all the answers
Which drug class inhibits dopamine in the trigger zone and histamine and muscarinic receptor activation in the brain?
Which drug class inhibits dopamine in the trigger zone and histamine and muscarinic receptor activation in the brain?
Signup and view all the answers
What impact can antacids have on the absorption of certain drugs?
What impact can antacids have on the absorption of certain drugs?
Signup and view all the answers
Which drug(s) discussed in the lecture have potential anticholinergic side effects?
Which drug(s) discussed in the lecture have potential anticholinergic side effects?
Signup and view all the answers
Why are phosphodiesterase-5 inhibitors contraindicated with the use of nitrates?
Why are phosphodiesterase-5 inhibitors contraindicated with the use of nitrates?
Signup and view all the answers
What are important components of patient education for a patient starting an alpha-adrenergic antagonist for BPH?
What are important components of patient education for a patient starting an alpha-adrenergic antagonist for BPH?
Signup and view all the answers
What are indications for the drugs listed in the above section with the exemplar list?
What are indications for the drugs listed in the above section with the exemplar list?
Signup and view all the answers
Which medication is indicated for inflammatory bowel disease?
Which medication is indicated for inflammatory bowel disease?
Signup and view all the answers
Which medication is a schedule V controlled medication with opioid and anticholinergic components?
Which medication is a schedule V controlled medication with opioid and anticholinergic components?
Signup and view all the answers
Which medication is used as the first-line treatment for chronic constipation and for bowel preparation?
Which medication is used as the first-line treatment for chronic constipation and for bowel preparation?
Signup and view all the answers
Which medication is a dopamine receptor antagonist used for GERD, delayed gastric emptying, and gastroparesis?
Which medication is a dopamine receptor antagonist used for GERD, delayed gastric emptying, and gastroparesis?
Signup and view all the answers
Which medication is a uroselective alpha 1A receptor antagonist with specific indications, mechanisms of action, and adverse effects, requiring consideration prior to cataract surgery?
Which medication is a uroselective alpha 1A receptor antagonist with specific indications, mechanisms of action, and adverse effects, requiring consideration prior to cataract surgery?
Signup and view all the answers
Alpha-adrenergic antagonists should be avoided if the patient is also taking alpha blockers
Alpha-adrenergic antagonists should be avoided if the patient is also taking alpha blockers
Signup and view all the answers
Antacids can only inhibit the absorption of certain drugs like antibiotics
Antacids can only inhibit the absorption of certain drugs like antibiotics
Signup and view all the answers
Phosphodiesterase-5 inhibitors are contraindicated with nitrates due to the potential for hypotension
Phosphodiesterase-5 inhibitors are contraindicated with nitrates due to the potential for hypotension
Signup and view all the answers
Oxybutynin and solifenacin are the only drugs discussed in the lecture that have potential anticholinergic side effects
Oxybutynin and solifenacin are the only drugs discussed in the lecture that have potential anticholinergic side effects
Signup and view all the answers
Phenazopyridine is recommended for long-term use in patients with chronic urinary tract infections
Phenazopyridine is recommended for long-term use in patients with chronic urinary tract infections
Signup and view all the answers
Mirabegron and Vibegron are contraindicated in patients with uncontrolled hypertension.
Mirabegron and Vibegron are contraindicated in patients with uncontrolled hypertension.
Signup and view all the answers
Phenazopyridine should be used for more than 2 days due to its low risk of side effects.
Phenazopyridine should be used for more than 2 days due to its low risk of side effects.
Signup and view all the answers
Mirabegron and Vibegron may interact with digoxin, metoprolol, antipsychotics, and amphetamines.
Mirabegron and Vibegron may interact with digoxin, metoprolol, antipsychotics, and amphetamines.
Signup and view all the answers
Phenazopyridine may cause rare hemolytic anemia as an adverse effect.
Phenazopyridine may cause rare hemolytic anemia as an adverse effect.
Signup and view all the answers
Mirabegron and Vibegron have no known drug interactions.
Mirabegron and Vibegron have no known drug interactions.
Signup and view all the answers
Proton pump inhibitors achieve maximum acid suppression within 24 hours of starting the medication.
Proton pump inhibitors achieve maximum acid suppression within 24 hours of starting the medication.
Signup and view all the answers
Antacids taken on an empty stomach have a longer duration of action compared to when taken after a meal.
Antacids taken on an empty stomach have a longer duration of action compared to when taken after a meal.
Signup and view all the answers
Calcium carbonate (TUMS) may interact with tetracyclines, leading to decreased effectiveness of the antibiotic.
Calcium carbonate (TUMS) may interact with tetracyclines, leading to decreased effectiveness of the antibiotic.
Signup and view all the answers
Sucralfate forms a paste that binds to the upper GI tract ulcers for up to 12 hours.
Sucralfate forms a paste that binds to the upper GI tract ulcers for up to 12 hours.
Signup and view all the answers
Bismuth-based quadruple therapy for H. pylori infection involves the use of a PPI, bismuth subsalicylate, tetracycline, and metronidazole.
Bismuth-based quadruple therapy for H. pylori infection involves the use of a PPI, bismuth subsalicylate, tetracycline, and metronidazole.
Signup and view all the answers
Metoclopramide is a dopamine receptor agonist used for GERD, delayed gastric emptying, and gastroparesis.
Metoclopramide is a dopamine receptor agonist used for GERD, delayed gastric emptying, and gastroparesis.
Signup and view all the answers
Bismuth subsalicylate is contraindicated for indigestion, abdominal cramps, and diarrhea prevention.
Bismuth subsalicylate is contraindicated for indigestion, abdominal cramps, and diarrhea prevention.
Signup and view all the answers
Loperamide, an opioid derivative, has laxative properties and carries risks of dizziness, constipation, and cardiac effects.
Loperamide, an opioid derivative, has laxative properties and carries risks of dizziness, constipation, and cardiac effects.
Signup and view all the answers
Polyethylene glycol (Miralax) is a stimulant laxative used as the first-line treatment for chronic constipation and for bowel preparation.
Polyethylene glycol (Miralax) is a stimulant laxative used as the first-line treatment for chronic constipation and for bowel preparation.
Signup and view all the answers
Finasteride is used for BPH and male pattern baldness, with potential adverse effects including sexual and gastrointestinal effects.
Finasteride is used for BPH and male pattern baldness, with potential adverse effects including sexual and gastrointestinal effects.
Signup and view all the answers
Study Notes
Gastrointestinal Medications and Urological Treatments
- Metoclopramide is a dopamine receptor antagonist used for GERD, delayed gastric emptying, and gastroparesis, but has adverse effects and contraindications.
- Bismuth subsalicylate is indicated for indigestion, abdominal cramps, and diarrhea prevention, but has potential adverse effects and contraindications, including salicylate allergy.
- Loperamide, an opioid derivative, has antisecretory properties but carries risks of dizziness, constipation, and cardiac effects, with specific contraindications and cautions.
- Diphenoxylate/atropine (Lomotil) is a schedule V controlled medication with opioid and anticholinergic components, presenting potential adverse effects and cautions, including atropinism.
- Bulk-forming laxatives such as psyllium and docusate sodium have specific mechanisms of action, indications, and adverse effects, including the risk of obstruction and diarrhea.
- Polyethylene glycol (Miralax) is an osmotic laxative, used as the first-line treatment for chronic constipation and for bowel preparation, but carries risks of fluid and electrolyte imbalance.
- Glycerin and bisacodyl are used for intermittent constipation, with specific mechanisms of action and adverse effects, and bisacodyl is reserved for specific cases and should not be used long term.
- Sulfasalazine, a prototype ASA, is indicated for inflammatory bowel disease, with a dual molecule composition and specific mechanisms of action within the GI tract.
- Tamsulosin, a uroselective alpha 1A receptor antagonist, has specific indications, mechanisms of action, and adverse effects, requiring consideration prior to cataract surgery.
- Finasteride, a 5 alpha reductase inhibitor, is used for BPH and male pattern baldness, with specific mechanisms of action and adverse effects, including sexual and gastrointestinal effects.
- Sildenafil, a PDE 5 inhibitor, is used for BPH with ED symptoms, and additional pharmacological treatments may be added as irritative symptoms develop.
- Oxybutynin and solifenacin are anticholinergic medications used for overactive bladder and incontinence, with specific mechanisms of action, adverse effects, and contraindications, including cognitive effects and narrow-angle glaucoma.
Gastrointestinal Medications and Urological Treatments
- Metoclopramide is a dopamine receptor antagonist used for GERD, delayed gastric emptying, and gastroparesis, but has adverse effects and contraindications.
- Bismuth subsalicylate is indicated for indigestion, abdominal cramps, and diarrhea prevention, but has potential adverse effects and contraindications, including salicylate allergy.
- Loperamide, an opioid derivative, has antisecretory properties but carries risks of dizziness, constipation, and cardiac effects, with specific contraindications and cautions.
- Diphenoxylate/atropine (Lomotil) is a schedule V controlled medication with opioid and anticholinergic components, presenting potential adverse effects and cautions, including atropinism.
- Bulk-forming laxatives such as psyllium and docusate sodium have specific mechanisms of action, indications, and adverse effects, including the risk of obstruction and diarrhea.
- Polyethylene glycol (Miralax) is an osmotic laxative, used as the first-line treatment for chronic constipation and for bowel preparation, but carries risks of fluid and electrolyte imbalance.
- Glycerin and bisacodyl are used for intermittent constipation, with specific mechanisms of action and adverse effects, and bisacodyl is reserved for specific cases and should not be used long term.
- Sulfasalazine, a prototype ASA, is indicated for inflammatory bowel disease, with a dual molecule composition and specific mechanisms of action within the GI tract.
- Tamsulosin, a uroselective alpha 1A receptor antagonist, has specific indications, mechanisms of action, and adverse effects, requiring consideration prior to cataract surgery.
- Finasteride, a 5 alpha reductase inhibitor, is used for BPH and male pattern baldness, with specific mechanisms of action and adverse effects, including sexual and gastrointestinal effects.
- Sildenafil, a PDE 5 inhibitor, is used for BPH with ED symptoms, and additional pharmacological treatments may be added as irritative symptoms develop.
- Oxybutynin and solifenacin are anticholinergic medications used for overactive bladder and incontinence, with specific mechanisms of action, adverse effects, and contraindications, including cognitive effects and narrow-angle glaucoma.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
Test your knowledge of gastrointestinal medications and urological treatments with this quiz. Explore the indications, mechanisms of action, adverse effects, and contraindications of medications such as metoclopramide, bismuth subsalicylate, loperamide, tamsulosin, finasteride, and oxybutynin.
