Pharmacology of Antihistamines and Decongestants
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Questions and Answers

What elicits its antihistamine effects by selectively binding to peripheral H1 receptors?

  • Diphenhydramine
  • Clemastine
  • Desloratadine (correct)
  • Brompheniramine
  • Which is classified as a decongestant?

  • Levocetirizine (Xyzal)
  • Azelastine (Astelin)
  • Dextromethorphan (Delsym)
  • Oxymetazoline (Afrin) (correct)
  • What factors contribute to elderly clients being at higher risk of injury while taking antihistamines? (Select all that apply)

  • Diabetes
  • Visual impairment (correct)
  • Steady gait
  • Hearing loss (correct)
  • Hypertension
  • When developing the teaching plan for a patient receiving an antihistamine, which would the nurse include? (Select all that apply)

    <p>Advising the patient to avoid alcohol consumption</p> Signup and view all the answers

    Which of the following medications, if administered with pseudoephedrine, could increase risk of cardiac dysrhythmia?

    <p>MAO inhibitors</p> Signup and view all the answers

    What is the most important assessment the nurse should complete before the client leaves the clinic to purchase pseudoephedrine?

    <p>Obtain the client's blood pressure</p> Signup and view all the answers

    The nurse instructs the patient using a topical nasal decongestant to stop using the drug after which length of time?

    <p>3 days</p> Signup and view all the answers

    To promote sinus drainage, what medication might be ordered for a patient diagnosed with acute sinusitis?

    <p>Topical decongestants</p> Signup and view all the answers

    What type of medication would the nurse expect to find most commonly prescribed for chronic pharyngitis?

    <p>Antitussives</p> Signup and view all the answers

    Which of the following should a nurse include in a patient's teaching plan for antitussive use? (Select all that apply)

    <p>Avoid respiratory irritants during antitussive treatment</p> Signup and view all the answers

    Which interaction between a nasal decongestant and MAO inhibitors should the nurse warn the patient about?

    <p>Severe headache</p> Signup and view all the answers

    Which feature of the patient's medical history would be of concern for Ms. Carter prescribed fexofenadine?

    <p>She has a history of excessive alcohol use</p> Signup and view all the answers

    Which classification of drugs is commonly found in OTC combined cold medications?

    <p>Oral decongestants</p> Signup and view all the answers

    What elicits their pharmacological effect by reducing swelling in the nasal passages by vasoconstriction? (Select all that apply)

    <p>Oxymetazoline</p> Signup and view all the answers

    Which should be observed during ongoing assessment of a client taking a decongestant? (Select all that apply)

    <p>Therapeutic effect</p> Signup and view all the answers

    While using a decongestant, a client should be instructed to call the physician if which occur? (Select all that apply)

    <p>Symptoms do not improve in seven days</p> Signup and view all the answers

    Study Notes

    Antihistamines

    • Desloratadine selectively binds to peripheral H1 receptors, producing antihistamine effects.
    • First-generation antihistamines like diphenhydramine, brompheniramine, and clemastine can cause sedation.
    • Elderly clients may be at higher injury risk when taking antihistamines due to factors like hearing loss and visual impairment.

    Decongestants

    • Oxymetazoline is classified as a nasal decongestant.
    • Pseudoephedrine may cause cardiac dysrhythmias when taken with MAO inhibitors.
    • Topical nasal decongestants should not be used for more than 3-5 days to prevent rebound congestion.

    Patient Education

    • Patients should avoid alcohol while on antihistamines and stay hydrated to combat dry mouth.
    • Antitussives require patient education about avoiding respiratory irritants and proper usage of medications.
    • Important to monitor effects of decongestants such as blood pressure and therapeutic outcomes.

    Common Medications

    • Fexofenadine is used for allergic rhinitis, but history of excessive alcohol use could be concerning.
    • OTC combined cold medications often include oral decongestants among other ingredients.
    • Phenylephrine and oxymetazoline reduce nasal swelling through vasoconstriction.

    Monitoring and Assessment

    • Patients taking decongestants should have ongoing assessments of blood pressure and congestion levels.
    • Call a physician if symptoms don’t improve after seven days or if a high fever develops while using a decongestant.

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    Description

    This quiz covers key concepts related to antihistamines and decongestants, focusing on their pharmacological effects, patient education, and safety considerations. Test your knowledge on common medications, their impacts on elderly clients, and essential monitoring practices. Perfect for students in a pharmacology course or healthcare professionals.

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