10 Questions
What is the primary target of fluoroquinolones in Gram (-) bacteria?
DNA gyrase (topoisomerase II)
Rifamycins selectively bind to which subunit of bacterial RNA polymerase?
ß subunit
What is the primary mode of action of rifamycins?
Inhibition of RNA transcription
Which antibiotic is specifically used to treat infections caused by Mycobacterium tuberculosis?
Rifampin
What is the primary target of fluoroquinolones in Gram (+) bacteria?
Topoisomerase IV
Polymyxin acts by disrupting which structure in bacterial cells?
Cytoplasmic membrane
What is the primary mode of action of polymyxins?
Disruption of cytoplasmic membrane
Which of the following antibiotics inhibits DNA synthesis?
Fluoroquinolones
What is the primary mode of action of fluoroquinolones?
Inhibition of DNA synthesis
Daptomycin acts by which mode of action?
Selective disruption of cytoplasmic membrane
Understand how antibiotics work by inhibiting nucleic acid synthesis. Learn about polymyxin and other membrane-active agents, their effects on mammalian cells, and their uses as antiseptics and disinfectants.
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