Pharmacology: Losartan Potassium Flashcards
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Questions and Answers

What is the generic name of the drug?

  • Amlodipine
  • Losartan Potassium (correct)
  • Ibuprofen
  • Lisinopril

What class of drug is Losartan Potassium?

  • ARB (correct)
  • ACE inhibitor
  • Beta-blocker
  • Calcium channel blocker

What is the mechanism of action (MOA) of Losartan?

Blocks the conversion of A1 to all; the effect is comparable to ACE inhibitors, however ARBs do not cause a cough.

What are the indications for using Losartan?

<p>Hypertension</p> Signup and view all the answers

What are the contraindications for Losartan?

<p>Hypersensitivity to losartan, pregnancy (category C in the first trimester, category D in the second and third trimesters), lactation.</p> Signup and view all the answers

What are some adverse effects of Losartan?

<p>Chest pain, fatigue, hypoglycemia.</p> Signup and view all the answers

What nursing implications should be considered when administering Losartan?

<p>Monitor BP at drug trough, monitor drug effectiveness, especially in African-Americans when used as monotherapy, and consider dividing the dose if inadequate response occurs.</p> Signup and view all the answers

What is the route of administration for Losartan?

<p>PO</p> Signup and view all the answers

What is the peak effect time for Losartan?

<p>6 hours</p> Signup and view all the answers

What is the duration of effectiveness for Losartan?

<p>24 hours</p> Signup and view all the answers

What patient education should be provided for Losartan?

<p>Notify physician of symptoms of hypotension, pregnancy, and do not breastfeed while taking this drug.</p> Signup and view all the answers

Study Notes

Losartan Potassium Overview

  • Generic name: Losartan Potassium
  • Classification: Angiotensin II Receptor Antagonist (ARB)

Mechanism of Action

  • Blocks the conversion of Angiotensin I to Angiotensin II
  • Comparable effects to ACE inhibitors without causing cough

Indications

  • Primary use for treating hypertension (high blood pressure)

Contraindications

  • Hypersensitivity to Losartan
  • Not safe during pregnancy (Category C in first trimester, Category D in second and third trimesters)
  • Use during lactation is not recommended

Adverse Effects

  • Possible side effects include chest pain, fatigue, and hypoglycemia
  • NSAIDs may diminish the antihypertensive effects of ARBs

Nursing Implications

  • Monitor blood pressure at drug trough (before scheduled doses)
  • Assess drug effectiveness, particularly in African-American populations when used as monotherapy
  • In cases of inadequate response, consider dividing daily dosage into two doses

Route of Administration

  • Taken orally (PO)

Onset, Peak, and Duration

  • Onset: Not applicable
  • Peak effect occurs in 6 hours
  • Duration of action lasts for 24 hours

Patient Education

  • Report symptoms of hypotension (e.g., dizziness, fainting) to a physician
  • Notify healthcare provider if pregnancy occurs while on medication
  • Advise against breastfeeding during treatment with Losartan

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Test your knowledge of Losartan Potassium with these flashcards. The quiz covers its classification, mechanism of action, indications, and contraindications. Perfect for students and professionals in the field of pharmacology.

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