Pharmacology: Losartan Potassium Flashcards
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Questions and Answers

What is the generic name of the drug?

  • Amlodipine
  • Losartan Potassium (correct)
  • Ibuprofen
  • Lisinopril
  • What class of drug is Losartan Potassium?

  • ARB (correct)
  • ACE inhibitor
  • Beta-blocker
  • Calcium channel blocker
  • What is the mechanism of action (MOA) of Losartan?

    Blocks the conversion of A1 to all; the effect is comparable to ACE inhibitors, however ARBs do not cause a cough.

    What are the indications for using Losartan?

    <p>Hypertension</p> Signup and view all the answers

    What are the contraindications for Losartan?

    <p>Hypersensitivity to losartan, pregnancy (category C in the first trimester, category D in the second and third trimesters), lactation.</p> Signup and view all the answers

    What are some adverse effects of Losartan?

    <p>Chest pain, fatigue, hypoglycemia.</p> Signup and view all the answers

    What nursing implications should be considered when administering Losartan?

    <p>Monitor BP at drug trough, monitor drug effectiveness, especially in African-Americans when used as monotherapy, and consider dividing the dose if inadequate response occurs.</p> Signup and view all the answers

    What is the route of administration for Losartan?

    <p>PO</p> Signup and view all the answers

    What is the peak effect time for Losartan?

    <p>6 hours</p> Signup and view all the answers

    What is the duration of effectiveness for Losartan?

    <p>24 hours</p> Signup and view all the answers

    What patient education should be provided for Losartan?

    <p>Notify physician of symptoms of hypotension, pregnancy, and do not breastfeed while taking this drug.</p> Signup and view all the answers

    Study Notes

    Losartan Potassium Overview

    • Generic name: Losartan Potassium
    • Classification: Angiotensin II Receptor Antagonist (ARB)

    Mechanism of Action

    • Blocks the conversion of Angiotensin I to Angiotensin II
    • Comparable effects to ACE inhibitors without causing cough

    Indications

    • Primary use for treating hypertension (high blood pressure)

    Contraindications

    • Hypersensitivity to Losartan
    • Not safe during pregnancy (Category C in first trimester, Category D in second and third trimesters)
    • Use during lactation is not recommended

    Adverse Effects

    • Possible side effects include chest pain, fatigue, and hypoglycemia
    • NSAIDs may diminish the antihypertensive effects of ARBs

    Nursing Implications

    • Monitor blood pressure at drug trough (before scheduled doses)
    • Assess drug effectiveness, particularly in African-American populations when used as monotherapy
    • In cases of inadequate response, consider dividing daily dosage into two doses

    Route of Administration

    • Taken orally (PO)

    Onset, Peak, and Duration

    • Onset: Not applicable
    • Peak effect occurs in 6 hours
    • Duration of action lasts for 24 hours

    Patient Education

    • Report symptoms of hypotension (e.g., dizziness, fainting) to a physician
    • Notify healthcare provider if pregnancy occurs while on medication
    • Advise against breastfeeding during treatment with Losartan

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    Description

    Test your knowledge of Losartan Potassium with these flashcards. The quiz covers its classification, mechanism of action, indications, and contraindications. Perfect for students and professionals in the field of pharmacology.

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