Pharmacology Lecture: Drug Therapy of Acid-related GIT Disorders-1

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12 Questions

Which enzyme is involved in the metabolism of PPIs?

CYP3A4

What adverse effect on the gastrointestinal tract can be caused by PPIs?

Nausea

Which condition in animals has been associated with hypochlorhydria caused by PPIs?

Gastric tumors

What is one of the adverse effects on the central nervous system that can result from PPI use?

Headache

What is the mechanism of action of Vonoprazan?

Inhibits H+/K+ ATPase by forming an ionic bond

What advantage do P-CABs have over PPIs in terms of food intake?

Absorption is not affected by food intake

How do P-CABs compare to PPIs in terms of control of nocturnal symptoms?

P-CABs have better control

Which of the following PPI adverse effects affect the Central Nervous System?

Headache

What is one of the adverse effects on the Central Nervous System resulting from PPI use?

Headache

Which of the following is an advantage of P-CABs over PPIs in terms of therapeutic response onset?

Rapid onset of therapeutic response within 2 hours

What is one notable advantage of P-CABs over PPIs regarding food intake?

Not affected by food intake

How do P-CABs compare to PPIs regarding Vitamin B12 deficiency?

No effect on Vitamin B12 levels

Learn about the mechanism of action, indications, and adverse effects of drugs used in managing acid-related gastrointestinal disorders such as Peptic Ulcer. Get insights into the types of ulcers like Duodenal ulcer and Gastric ulcer caused by factors like increased HCl levels and H.Pylori infection.

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