Drugs Used in Acid-Peptic Diseases
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Questions and Answers

What stimulates acid secretion from the proton pump on the canalicular surface of parietal cells?

  • Increase in cytosolic calcium due to acetylcholine or gastrin binding (correct)
  • Release of histamine by ECL cells
  • Inhibition of protein kinases
  • Decrease in cytosolic calcium due to acetylcholine or gastrin binding

    • Which factor is recognized as a causative factor for acid-peptic diseases?

  • Consumption of spicy food
  • Infection with gram-negative Helicobacter pylori (correct)
  • Excessive intake of vitamin C
  • Consumption of high-fiber diet

    • What is the main source for histamine release in the gastrointestinal tract?

  • Chief cells
  • Parietal cells
  • Goblet cells
  • Enterochromaffin-like (ECL) cells (correct)

    • Which approach is used in the treatment of acid-peptic diseases to eradicate H. pylori infection?

    <p>Eradicating the H. pylori infection</p> Signup and view all the answers

    What do parietal cells contain receptors for?

    <p>Gastrin, histamine (H2), and acetylcholine (muscarinic, M3)</p> Signup and view all the answers

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