5 Questions
What stimulates acid secretion from the proton pump on the canalicular surface of parietal cells?
Increase in cytosolic calcium due to acetylcholine or gastrin binding
Which factor is recognized as a causative factor for acid-peptic diseases?
Infection with gram-negative Helicobacter pylori
What is the main source for histamine release in the gastrointestinal tract?
Enterochromaffin-like (ECL) cells
Which approach is used in the treatment of acid-peptic diseases to eradicate H. pylori infection?
Eradicating the H. pylori infection
What do parietal cells contain receptors for?
Gastrin, histamine (H2), and acetylcholine (muscarinic, M3)
Learn about the drugs used in the treatment of acid-peptic diseases including gastroesophageal reflux, peptic ulcer, and stress-related mucosal injury. Understand the major causative factors and treatment approaches for these conditions.
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