10 Questions
What is the primary cause of iron deficiency, leading to chronic anemia?
Gastrointestinal bleeding
Which receptor do second-generation antihistamines, such as fexofenadine and loratidine, primarily target?
H1 receptor
Which vitamin is a cofactor in the synthesis of DNA and is used for the treatment of naturally occurring pernicious anemia?
Vitamin B12
Which type of anemia is treated with folic acid?
Megaloblastic anemia
What is the primary difference between first-generation and second-generation antihistamines?
First-generation causes sedation, while second-generation does not.
Which of the following is NOT a mechanism of histamine action?
Activation of H1-receptor leading to increased heart rate
Which of the following is a clinical use of histamine?
Gastric acid secretion test
What is the main effect of histamine?
Bronchoconstriction
Which condition contraindicates the use of histamine?
Asthma
What is the main source of histamine release in anaphylactic shock and allergic conditions?
Basophils
This quiz covers the pharmacological aspects of histamine and antihistamine drugs, focusing on their role as local hormones in the body, their release during allergic conditions, and their mechanism of action on H1-receptor. It also includes information on mast cell injury and degranulation.
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