18 Questions
Which type of bioassay uses microorganisms to determine the antimicrobial potency of antibiotics?
Antimicrobial bioassay
What is the gold standard assay mentioned in the text for determining antimicrobial potency?
Disk diffusion assay
Which method is used in the Antifungal bioassay that involves the use of fungal spores?
Paper disc method
What are examples of assays that involve determining concentrations like MIC, MBC, and MBSC?
Minimum Inhibitory Concentration
Which type of assay evaluates cytokine release and cell maturation using cells from whole bone marrow?
Antimicrobial assay
What type of agents are involved in antimitotic assays based on their impact on the mitotic cycle?
Pharmacological agents
What is the main purpose of a bioassay in pharmacology?
To estimate the concentration of a substance in a biological system
Which term best describes a bioassay that involves applying a specific substance to a biological organism to observe physical, biological, and chemical changes?
Indirect Assay
What is the key difference between Quantal and Graded assays in bioassays?
Graded assays measure responses in categories while Quantal assays measure continuous responses
In indirect bioassays, which method involves determining the concentration of a substance by comparing its effects with those of standard concentrations?
Interpolation
Which of the following is an example of an Existing and Emerging Bioassay as mentioned in the text?
Reporter-based biochemical bioassays
What type of bioassay would involve using biosensors to detect binding interactions between biological molecules?
Biosensor-based binding bioassays
What is the typical subject in a bioassay?
An animal or tissue
Which of the following is not a common agent in a bioassay?
Geological agent
In a bioassay, what is the purpose of the test substance?
To observe the response of the subject
What types of responses are common in bioassays?
Binary, continuous, or characteristic responses
In the principle of bioassay, why is it important for the active agent to show a similar response in different animal species?
To ensure consistent response measurement
What distinguishes quantitative assays from qualitative assays?
Quantitative assays provide numerical analysis, while qualitative assays do not.
Explore components, structure, principles, and types of bioassays in pharmacology laboratory. Learn about direct and indirect assays, response/graded assays, pharmacological assays, and existing/emerging bioassays.
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