Introduction to Bioassay

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Questions and Answers

What is the purpose of a bioassay?

  • To identify the chemical composition of a substance
  • To measure the physical properties of a substance
  • To determine the potency of a substance by measuring its effect on living organisms (correct)
  • To determine the shelf life of a substance

What is the primary purpose of a bioassay?

  • To determine the chemical composition of a substance
  • To analyze the microbial contamination of a substance
  • To measure the potency of a substance by its effect on living organisms (correct)
  • To assess the physical properties of a substance

What is a dose-response curve in bioassay?

  • A measure of the toxicity level of a substance
  • A measure of the speed at which an organism responds to a substance
  • A graphical representation of the relationship between dose of a substance and the response it produces in an organism (correct)
  • The chemical structure of a substance used in bioassay

What is an example of an endpoint in bioassay?

<p>Cell death (A)</p> Signup and view all the answers

What is an example of an endpoint commonly used in bioassays?

<p>Cell viability (A)</p> Signup and view all the answers

What is an advantage of using a bioassay over chemical analysis to measure potency?

<p>Bioassays account for potential interactions with complex biological systems (C)</p> Signup and view all the answers

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Study Notes

Bioassay Purpose and Concepts

  • The primary purpose of a bioassay is to determine the potency or concentration of a substance, such as a drug or hormone, by measuring its effect on living organisms or tissues.

Dose-Response Curve

  • A dose-response curve in bioassay is a graphical representation of the relationship between the dose of a substance and the resulting biological response or effect.

Endpoint in Bioassay

  • An endpoint in bioassay refers to the specific biological response or effect being measured, such as death, growth, or changes in behavior.
  • An example of an endpoint commonly used in bioassays is lethality, where the dose of a substance required to cause death in a certain percentage of test organisms is measured.

Advantage of Bioassay over Chemical Analysis

  • An advantage of using a bioassay over chemical analysis to measure potency is that bioassays can detect the biological activity of a substance, which may not be fully captured by chemical analysis.

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