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Questions and Answers
What is the role of NO in the vasodilating effect of SNP?
What is the role of NO in the vasodilating effect of SNP?
- Increases calcium uptake by the smooth endoplasmic reticulum
- Inhibits calcium entry into vascular smooth muscle cells
- Activates the enzyme guanylate cyclase, leading to increased cGMP (correct)
- Dissociates immediately from oxyhemoglobin and forms methemoglobin
How does SNP differ from nitroglycerin in terms of NO generation?
How does SNP differ from nitroglycerin in terms of NO generation?
- SNP forms methemoglobin while releasing NO
- Nitroglycerin spontaneously generates NO
- SNP interacts with oxyhemoglobin to release NO
- Nitroglycerin requires thio-containing compounds to generate NO (correct)
What is the main mechanism by which SNP produces vasodilation?
What is the main mechanism by which SNP produces vasodilation?
- Activating guanylate cyclase and increasing cGMP (correct)
- Increasing methemoglobin formation
- Releasing cyanide and NO
- Increasing calcium uptake by smooth endoplasmic reticulum
