Pharmacology IV Infusion Effects Quiz
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Questions and Answers

What is the role of NO in the vasodilating effect of SNP?

  • Increases calcium uptake by the smooth endoplasmic reticulum
  • Inhibits calcium entry into vascular smooth muscle cells
  • Activates the enzyme guanylate cyclase, leading to increased cGMP (correct)
  • Dissociates immediately from oxyhemoglobin and forms methemoglobin
  • How does SNP differ from nitroglycerin in terms of NO generation?

  • SNP forms methemoglobin while releasing NO
  • Nitroglycerin spontaneously generates NO
  • SNP interacts with oxyhemoglobin to release NO
  • Nitroglycerin requires thio-containing compounds to generate NO (correct)
  • What is the main mechanism by which SNP produces vasodilation?

  • Activating guanylate cyclase and increasing cGMP (correct)
  • Increasing methemoglobin formation
  • Releasing cyanide and NO
  • Increasing calcium uptake by smooth endoplasmic reticulum
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