Podcast
Questions and Answers
What is a primary function of interferons?
What is a primary function of interferons?
Which of the following is a potential side effect to monitor for when administering interleukins?
Which of the following is a potential side effect to monitor for when administering interleukins?
What should patients receiving interferons be instructed to report immediately?
What should patients receiving interferons be instructed to report immediately?
Which laboratory values should be monitored during treatment with interleukins?
Which laboratory values should be monitored during treatment with interleukins?
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What symptom might indicate pancreatitis in a patient receiving interferons?
What symptom might indicate pancreatitis in a patient receiving interferons?
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Study Notes
Interferons
- Interferon alfa-2b (Intron A) and peginterferon alfa-2b (PegIntron, Sylatron) are examples of interferons.
- Interferons bind to receptors to inhibit cell growth.
- Monitor patients for cardiovascular status, pancreatitis, neuropsychiatric disorders, and colitis.
- Instruct patients to notify their healthcare provider immediately if they experience signs of infection, lower back or side pain, painful or difficult urination, bleeding, suicidal thoughts or attempts, new or worsening anxiety, depression, agitation, or aggressive or violent behavior.
Interleukins
- Aldesleukin (Proleukin) is an example of an interleukin.
- Interleukins stimulate T cells, B cells, and NK cells to attack cancer cells.
- Monitor patients for complete blood count with differential, platelet count, electrolytes, kidney, liver, and thyroid function.
- Monitor cardiovascular status continuously during transfusion.
- Monitor for capillary leak syndrome (hypotension, hypovolemia, edema, ascites, pleural effusion).
- Monitor respiratory status, weight daily, and skin for the development of rash or blisters.
- Monitor for signs of infection.
- Instruct patients to notify their healthcare provider if they develop symptoms of infection, liver dysfunction, unusual bleeding or bruising, or increased fatigue.
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Description
This quiz tests your knowledge on interferons and interleukins, including their uses, monitoring requirements, and potential side effects. Understand how these biological agents work in immunotherapy and their impact on patient care. Be prepared to identify the examples and critical monitoring parameters essential for safety.
