Pharmacology III PLC 401: Cancer Chemotherapy
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Pharmacology III PLC 401: Cancer Chemotherapy

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Questions and Answers

During which phase of the cell cycle does the DNA replicate?

  • G1 phase
  • M phase
  • G2 phase
  • S phase (correct)

    • Which protein is responsible for unwinding an organism's genetic material during DNA replication?

  • Helicase (correct)
  • DNA polymerase
  • DNA topoisomerase
  • DNA ligase

    • What is the main function of DNA ligase during DNA replication?

  • Joining DNA fragments to form a single, unbroken molecule (correct)
  • Forming sister chromatids
  • Unwinding DNA strands
  • Adding nucleotides to the growing DNA strand

    • Which phase of mitosis involves the separation of chromosomes and the elongation of the cell?

    <p>Anaphase</p> Signup and view all the answers

    What is the primary function of DNA topoisomerases during DNA replication?

    <p>Relaxing and supercoiling DNA</p> Signup and view all the answers

    What is the primary purpose of chemotherapy in the treatment of neoplastic disease?

    <p>Inhibit or destroy specific disease-causing agents</p> Signup and view all the answers

    At what stage does a tumor become clinically detectable?

    <p>When there is a mass of 10^9 cells</p> Signup and view all the answers

    What do we call cells that can either be non-dividing and terminally differentiated, continually proliferating, or at rest and may be recruited into the cell cycle?

    <p>Stem cells</p> Signup and view all the answers

    What should students be able to do by the end of the lecture according to the intended learning outcomes (ILOs)?

    <p>Recall key elements of the cell cycle</p> Signup and view all the answers

    What is the use of drugs in the treatment of neoplastic disease also known as?

    <p>Chemotherapy</p> Signup and view all the answers

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