Pharmacology for Heart Failure Management
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Questions and Answers

What is the primary effect of diuretic therapy?

  • Increasing urine production (correct)
  • Enhancing renal function
  • Reducing blood pressure
  • Lowering cholesterol levels
  • What should clients newly diagnosed with hyperlipidemia understand about their treatment?

  • Diet changes can completely replace medication
  • Statin drugs are the most common prescribed medications (correct)
  • They will only need medication temporarily
  • All medications are side-effect free
  • What is a significant consideration for patients prescribed statin medications?

  • They should stop the medication after six months.
  • They should only use them when levels are high.
  • Continuous use may be required for life. (correct)
  • Statins must be taken with food for best results.
  • Which type of medication is bumetanide classified as?

    <p>Diuretic</p> Signup and view all the answers

    What is the primary goal of anti-cholesterol drugs?

    <p>Lower LDL levels</p> Signup and view all the answers

    What dietary recommendation should clients with heart failure follow to manage their condition effectively?

    <p>Follow a low sodium diet and monitor fluid intake.</p> Signup and view all the answers

    Decreasing which of the following can lead to increased cardiac output in heart failure patients?

    <p>Afterload to improve ventricular performance.</p> Signup and view all the answers

    Which statement accurately reflects a critical aspect of managing heart failure?

    <p>Sodium restriction is crucial to decrease fluid retention.</p> Signup and view all the answers

    In the context of heart failure management, what is the primary purpose of loop diuretics?

    <p>To decrease fluid overload and manage heart strain.</p> Signup and view all the answers

    Which of the following factors is NOT directly related to dietary recommendations for heart failure patients?

    <p>Daily exercise and activity level.</p> Signup and view all the answers

    What is the primary purpose of alteplase in relation to central lines?

    <p>To dissolve clots in the central line</p> Signup and view all the answers

    What class of medication is furosemide, and what is a key administration consideration?

    <p>It is a loop diuretic; push slowly to avoid hearing loss.</p> Signup and view all the answers

    Which of the following statements about atorvastatin is accurate?

    <p>It inhibits HMG-CoA reductase which can lead to muscle pain.</p> Signup and view all the answers

    What is the role of PCSK9 inhibitors in cholesterol management?

    <p>They block the production of LDL cholesterol.</p> Signup and view all the answers

    Which symptom is NOT associated with adverse effects of atorvastatin?

    <p>Weight gain</p> Signup and view all the answers

    Study Notes

    Diuretic Therapy

    • A desired effect of diuretic therapy is increased urination (polyuria).

    Anti-Cholesterol Drugs

    • The goal of anti-cholesterol drugs is to lower LDL levels.

    Hyperlipidemia Teaching

    • Lifestyle changes may help avoid medication for hyperlipidemia.
    • Statin drugs are the most common medication for hyperlipidemia.
    • Statin medications may be needed for life.

    Bumetanide

    • Bumetanide is a loop diuretic.

    Heart Failure Management

    • Clients with heart failure should follow a low-sodium diet and monitor fluid intake.

    Lidocaine Side Effects

    • An adverse effect of IV lidocaine is central nervous system (CNS) toxicity, which can manifest as confusion and psychosis.
    • Lidocaine can cause numbness and tingling as a side effect.

    Fluid Overload

    • Fluid overload from IV crystalloid administration can lead to heart failure.

    Aspirin and Apixaban

    • Aspirin should not be combined with apixaban.

    Alteplase

    • Alteplase is a thrombolytic medication used to dissolve clots (if a clot is suspected).

    PCSK9 Inhibitors

    • Monoclonal antibody PCSK9 inhibitors block LDL cholesterol production.

    Furosemide Administration

    • Furosemide should be administered slowly to avoid hearing loss.
    • Furosemide is a loop diuretic.

    Right Heart Failure

    Atorvastatin

    • Atorvastatin inhibits HMG-CoA reduction.
    • Side effects include severe muscle pain, weakness, and dark urine.

    Lipid Panel

    • A lipid panel should be ordered before statin medication.
    • Clients taking atorvastatin need regular lipid checks.
    • Atorvastatin is used for hyperlipidemia and can be used for preventing cardiovascular disease in clients with high blood pressure, diabetes, or smokers.
    • Assess the client's learning ability before client education.
    • Atorvastatin can cause rhabdomyolysis, hepatotoxicity (evaluated by ALT/AST levels)
    • Common medication for elevated cholesterol: (ALT, AST)

    Cholestyramine

    • Reduce serum cholesterol and LDL levels
    • Give with 60-80 ml of liquid
    • 2 hours before or 4 hours after medication

    Gemfibrozil

    • Increases HDL and reduces VLDL.
    • Take with food to prevent heartburn.

    Ezetimibe

    • Lowers cholesterol.
    • Can cause angioedema.

    Alirocumab

    • Binds to LDL receptors on the liver
    • Used for hypercholesterolemia
    • Causes flu-like symptoms
    • Given subcutaneously (SQ)

    Rivaroxaban

    • Administered orally.
    • Antidote is andexanet alfa.
    • Does not require INR monitoring.
    • System clears within 1-2 days after stopping.

    Therapeutic Response to Alirocumab

    • Decreases LDL levels.

    Ezetimibe

    • A selective cholesterol absorption inhibitor.
    • Nasopharyngitis is an adverse effect.

    Metoprolol

    • Slows heart rate and decreases blood pressure.
    • Clients should not stop taking it abruptly.

    Lisinopril

    • Clients taking ACE inhibitors should not double the dose if they miss a dose.
    • Pregnancy is a contraindication for lisinopril use.

    Propranolol (Beta Blocker)

    • Treats chest pain, anxiety, and high blood pressure.
    • Inform clients not to drive until they know how the medication affects them.

    Amiodarone (Antiarrhythmic)

    • Used for atrial and ventricular dysrhythmias.
    • Half-life up to 50 days.
    • Clients should be instructed on reliable forms of birth control.
    • Monitor potassium levels.

    Milrinone

    • Increases myocardial contractility and cardiac output.
    • Used for advanced/acute heart failure.
    • Continuous ECG monitoring is needed.

    Digoxin

    • Cardiac glycoside.

    Verapamil

    • Calcium channel blocker used to treat dysrhythmias.
    • Clients should avoid grapefruit juice.

    Heparin

    • aPTT is monitored.

    Warfarin

    • Contraindicated with ginger and most antibiotics.
    • Monitor PT and INR.
    • Clients should not increase broccoli intake.
    • Take medication at the same time every day.
    • INR can be 2–3 times higher than normal (0.9–1.1).
    • Vitamin K is used as a reversal agent.

    Clopidogrel

    • Antiplatelet.
    • Assess for bleeding and bruising before administration.

    Nitroglycerin

    • A common side effect is headache.
    • Heart rate and blood pressure should be monitored before administration.

    Carvedilol

    • Monitor heart rate and blood pressure before administering.

    Enalapril, Enoxaparin

    • Enalapril is an ACE inhibitor for hypertension and heart failure.
    • Enoxaparin is a low molecular weight heparin.

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    Description

    This quiz covers essential pharmacological treatments and considerations for heart failure management, including diuretics, anti-cholesterol drugs, and thrombolytics. It also addresses side effects and medication interactions critical for effective patient care.

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