Pharmacology: Drugs Affecting Coagulation & Bleeding

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10 Questions

What is the main indication for the use of fibrinolytic drugs?

Acute Myocardial Infarction

What is the mechanism of action of aspirin on platelet aggregation?

Acetylation of COX1 and TX-synthase

What is the duration of aspirin-induced antiplatelet effect?

5-7 days

What is the primary use of anti-platelet drugs?

Prevention of thromboembolic disorders

What is the result of damage to vascular endothelium?

Release of proaggregatory and vasoconstrictor mediators

What is the primary mechanism of action of fibrinolytic drugs?

Activation of the fibrinolytic system

What is the main adverse effect of fibrinolytic drugs?

Bleeding

What is the indication for the use of Vit K1-specific antidote?

Hemorrhage due to warfarin

What is the teratogenic effect of warfarin?

Both A and B

What is the primary site of action of aspirin?

Portal circulation

This quiz covers the pharmacology of drugs that affect coagulation, bleeding, and thrombosis, including anticoagulants, styptics, antiplatelets, and thrombolytics. It also explores their clinical uses and adverse effects.

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