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Pharmacology: Disopyramide and Quinidine

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Pharmacology: Disopyramide and Quinidine

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Questions and Answers

What is the therapeutic range of Disopyramide in ug/mL?

2-3

3-5 (correct)

7-10

5-7

What happens when Disopyramide levels exceed 10 ug/mL?

Bradycardia and atrioventricular node blockage (correct)

Dry mouth and constipation

Myocardial depression and arrhythmia

Tachycardia and hypertension

What is the purpose of analyzing serum levels of Disopyramide and Propranolol?

To diagnose the patient's underlying condition

To adjust the dosage of the medication (correct)

To assess the patient's diet and lifestyle

To monitor the patient's response to the medication

What is the time to peak concentration of Disopyramide?

1 hour Signup and view all the answers

What is Propranolol primarily prescribed for?

Atrial and ventricular arrhythmias Signup and view all the answers

Why are reference ranges for therapeutic levels of Disopyramide and Propranolol not harmonized?

Due to differences in reference books and sources Signup and view all the answers

What is the therapeutic level of Phenytoin?

10 to 20 ug/mL Signup and view all the answers

At what level does the toxic effect of Phenytoin occur?

Above 29 ug/mL Signup and view all the answers

What is the therapeutic level of Valproic Acid?

50 to 100 ug/mL Signup and view all the answers

What percentage of Valproic Acid is bound to protein?

93% Signup and view all the answers

What is the therapeutic level of Carbamazepine?

Not specified in the text Signup and view all the answers

What is the protein binding percentage of Phenytoin?

97% Signup and view all the answers

What is the main purpose of therapeutic drug monitoring?

To prevent toxicity and determine proper dosage Signup and view all the answers

Which type of medication is used to maintain normal heart function?

Cardiotropics Signup and view all the answers

What is the mechanism of action of Digoxin?

Inhibiting the Na-K ATPase pump in heart muscles Signup and view all the answers

Why is therapeutic drug monitoring required for certain medications?

To avoid toxic adverse effects and determine proper dosage Signup and view all the answers

Which of the following medications may require therapeutic drug monitoring?

Cardiotropics, antibiotics, and anti-epileptic drugs Signup and view all the answers

What is the benefit of knowing the concentration of a medication in the body?

It aids in avoiding toxic adverse effects and determining proper dosage Signup and view all the answers