Pharmacology: Disopyramide and Quinidine

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18 Questions

What is the therapeutic range of Disopyramide in ug/mL?

3-5

What happens when Disopyramide levels exceed 10 ug/mL?

Bradycardia and atrioventricular node blockage

What is the purpose of analyzing serum levels of Disopyramide and Propranolol?

To adjust the dosage of the medication

What is the time to peak concentration of Disopyramide?

1 hour

What is Propranolol primarily prescribed for?

Atrial and ventricular arrhythmias

Why are reference ranges for therapeutic levels of Disopyramide and Propranolol not harmonized?

Due to differences in reference books and sources

What is the therapeutic level of Phenytoin?

10 to 20 ug/mL

At what level does the toxic effect of Phenytoin occur?

Above 29 ug/mL

What is the therapeutic level of Valproic Acid?

50 to 100 ug/mL

What percentage of Valproic Acid is bound to protein?

93%

What is the therapeutic level of Carbamazepine?

Not specified in the text

What is the protein binding percentage of Phenytoin?

97%

What is the main purpose of therapeutic drug monitoring?

To prevent toxicity and determine proper dosage

Which type of medication is used to maintain normal heart function?

Cardiotropics

What is the mechanism of action of Digoxin?

Inhibiting the Na-K ATPase pump in heart muscles

Why is therapeutic drug monitoring required for certain medications?

To avoid toxic adverse effects and determine proper dosage

Which of the following medications may require therapeutic drug monitoring?

Cardiotropics, antibiotics, and anti-epileptic drugs

What is the benefit of knowing the concentration of a medication in the body?

It aids in avoiding toxic adverse effects and determining proper dosage

This quiz covers the pharmacological effects and properties of Disopyramide and Quinidine, including their toxic effects, excretion, and metabolism. Learn about the peak assessment and potential side effects of these medications.

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