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Y1S2 004 II Pharmacology: Cardiovascular

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18 Questions

What is the effect of propranolol on the heart rate?

Decrease

What is the mechanism of action of nitroglycerin?

Inhibition of smooth muscle contraction

What is the route of administration of propranolol?

Oral

What is the effect of nitroglycerin on blood pressure?

Decrease

What is the indication for the use of aspirin?

Reduce clot formation

What is the half-life of nitroglycerin when administered intravenously?

2.8 minutes

What is the primary mechanism of action of digoxin in the treatment of congestive cardiac failure?

Binding to the Na+/K+ ATPase pump and increasing intracellular sodium concentrations

What is the half-life of digoxin in the body?

36-40 hours

What is the effect of aspirin on prostacyclin (PGI2) synthesis?

Aspirin spares prostacyclin synthesis at lower doses

What is the primary use of digoxin in the treatment of cardiac conditions?

Congestive cardiac failure (CCF)

What is the outcome of digoxin's inhibition of the Na+/K+ ATPase pump in the heart?

Increased release of calcium from the sarcoplasmic reticulum

What is the effect of aspirin on platelet activation and aggregation?

Aspirin inhibits platelet activation and aggregation

What is the duration of action of aspirin at low dose?

7-9 days

What is the mechanism of action of heparin?

Inhibiting clotting factors: IIa, IXa, Xa, XIa and XIIa

What is the antidote for heparin overdose?

Protamine sulphate

What is the mechanism of action of warfarin?

Inhibiting the synthesis of clotting factors

What is the International Normalized Ratio (INR) used for?

Monitoring warfarin therapy

What is the treatment for warfarin-induced skin necrosis?

Heparin

Test your knowledge of cardiovascular drugs, including their functions and effects on the body. This quiz covers beta blockers, anticoagulants, and more.

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