Questions and Answers
What class of drugs does cromolyn sodium belong to?
chromones a.k.a cromoglycates
What do chromones or cromoglycates like cromolyn do?
stabilize airway mast cells, preventing degranulation and release of inflammatory mediators like histamine and leukotrienes
What are 2 clinical situations of asthma therapy where cromolyn sodium can be used?
prophylactic treatment prior to exposure to known triggers and chronic treatment as an anti-inflammatory controller agent in mild persistent asthma
What is the preferred initial anti-inflammatory controller therapy for mild persistent asthma?
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How are cromolyn sodium and short-acting beta agonists different?
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What are the implications of cromolyn sodium not reversing bronchospasm in treatment?
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Study Notes
Cromolyn Sodium Overview
- Belongs to the chromones class, also known as cromoglycates.
- Primarily used as a prophylactic and anti-inflammatory treatment in asthma management.
Mechanism of Action
- Stabilizes airway mast cells, preventing degranulation.
- Inhibits the release of inflammatory mediators, including histamine and leukotrienes.
Clinical Applications in Asthma Therapy
- Used prophylactically before exposure to known triggers such as pollen, exercise, or cold air.
- Functions as a chronic anti-inflammatory controller in mild persistent asthma.
Comparison with Other Medications
- Inhaled glucocorticoids are preferred as the initial anti-inflammatory therapy over cromolyn sodium.
- Short-acting beta agonists, like albuterol, reverse bronchospasm, while cromolyn sodium does not.
Treatment Implications
- Cromolyn sodium serves exclusively as a prophylactic treatment option for asthma, not for acute bronchospasm relief.
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Description
Test your knowledge on cromolyn sodium, a medication used in asthma therapy. This quiz covers its class, mechanisms, and clinical uses. Perfect for students studying pharmacology and drug therapies.
