Pharmacology Contributions and Curriculum Quiz
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Questions and Answers

What does pharmacokinetics focus on?

  • What a drug does to the body
  • How drugs interact with each other
  • What the body does to a drug (correct)
  • How drugs are formulated
  • Which of the following is NOT one of the four stages of pharmacokinetics?

  • Metabolism
  • Absorption
  • Therapy (correct)
  • Distribution
  • Which route of drug administration involves bypassing the gastrointestinal tract?

  • Inhalation
  • Rectal
  • Intravenous (IV) (correct)
  • Oral (PO)
  • What is the main focus of pharmacodynamics?

    <p>Drug action on the body</p> Signup and view all the answers

    Which phase of pharmacokinetics involves the movement of drug from site of administration to the bloodstream?

    <p>Absorption</p> Signup and view all the answers

    Why are there various routes of drug administration?

    <p>Based on physicochemical properties of drugs and therapeutic goals</p> Signup and view all the answers

    Who founded the Journal of Biological Chemistry in 1905?

    <p>Crystallized insulin</p> Signup and view all the answers

    Which of the following topics is covered in the UCLA Pharmacology Curriculum?

    <p>Pharmacokinetics</p> Signup and view all the answers

    In the grading policy, what percentage range indicates a 'Pass'?

    <p>50-35</p> Signup and view all the answers

    Which category of drugs are Xanthine derivatives classified under?

    <p>Sympathomimetic CNS stimulants</p> Signup and view all the answers

    What is the main focus of Pharmacodynamics in pharmacology principles?

    <p>Drugs affecting nervous systems</p> Signup and view all the answers

    What type of drugs are Anti-diabetic drugs classified as?

    <p>Anti-hypertensive drugs</p> Signup and view all the answers

    What is the primary mechanism of drug absorption through membranes?

    <p>Simple diffusion</p> Signup and view all the answers

    Which type of transport requires energy and transporters?

    <p>Active transport</p> Signup and view all the answers

    Which transporter family is known for unidirectional drug extrusion using ATP?

    <p>ABC transporter</p> Signup and view all the answers

    Which type of transport process has bidirectional drug uptake and extrusion without direct ATP usage?

    <p>Endocytosis</p> Signup and view all the answers

    What does endocytosis involve in terms of bringing materials into a cell?

    <p>Inward folding of the cell membrane</p> Signup and view all the answers

    Which type of transport is characterized by exceptionally large-sized drugs crossing the cell membrane?

    <p>Endocytosis</p> Signup and view all the answers

    Which type of drug is more lipid soluble and has more absorption?

    <p>Non-ionized drug</p> Signup and view all the answers

    What determines the degree of ionization of a drug?

    <p>pKa value</p> Signup and view all the answers

    Which equation is used to calculate the degree of ionization of a drug?

    <p><strong>Henderson-Hasselbalch equation</strong></p> Signup and view all the answers

    Which factor mainly determines the bioavailability of a drug?

    <p>Route of administration</p> Signup and view all the answers

    At what pH do the ionized and non-ionized forms of a drug exist in equal amounts?

    <p>pH = pKa</p> Signup and view all the answers

    When pH is less than the pKa of a drug, which forms predominate?

    <p><strong>Protonated forms</strong></p> Signup and view all the answers

    What happens to the bioavailability of an orally administered drug compared to an intravenously administered drug?

    <p>It decreases</p> Signup and view all the answers

    In terms of absorption, which type of drug is typically less absorbed due to being less lipid soluble?

    <p><strong>Ionized drug</strong></p> Signup and view all the answers

    What is the main effect of pH on absorption for weak acid drugs?

    <p>Optimal at pH 1-2</p> Signup and view all the answers

    Which type of drugs can be distributed from blood to tissues/cells?

    <p>'Free' (unbound) drugs only</p> Signup and view all the answers

    What is the bioavailability of intravenously administered medication?

    <p>100%</p> Signup and view all the answers

    Which factor influences the bioavailability of a drug dose administered orally?

    <p>First-pass metabolism</p> Signup and view all the answers

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