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Questions and Answers
Which mechanism of action involves the inhibition of RNA polymerase?
Which mechanism of action involves the inhibition of RNA polymerase?
What is a common adverse effect associated with certain antibiotics that causes discoloration in bodily fluids?
What is a common adverse effect associated with certain antibiotics that causes discoloration in bodily fluids?
Which drug mechanism involves directly binding to reverse transcriptase?
Which drug mechanism involves directly binding to reverse transcriptase?
Which drug is recognized for causing reversible optic neuritis and color blindness to red and green?
Which drug is recognized for causing reversible optic neuritis and color blindness to red and green?
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What mechanism describes a nucleoside analog that competitively blocks reverse transcriptase effects?
What mechanism describes a nucleoside analog that competitively blocks reverse transcriptase effects?
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Study Notes
Mechanisms of Action
- Enzymatic Inhibition: A prodrug inhibiting enoic reductase is listed.
- RNA Polymerase Inhibition: An inhibitor of RNA polymerase is mentioned.
- DNA-Dependent Inhibition: Inhibition of DNA-dependent processes is noted.
- Translational Alteration: An inhibitor of protein translation and membrane potential alteration is included.
Adverse Effects
- Fluid Color Changes: Orange coloration of fluids (urine, saliva, tears) is a potential side effect.
- Visual Disturbances: Reversible optic neuritis, leading to color blindness (red-green), is noted.
- Uric Acid Elevation: Increased blood uric acid levels are mentioned.
- Hepatotoxicity and Hemolytic Anemia: Hepatic damage and hemolytic anemia are potential side effects, especially in susceptible individuals.
Further Drug Actions
- Nucleoside Analog: A nucleoside analog that competitively inhibits reverse transcriptase.
- CCR5 Receptor Binding: A drug that binds to the CCR5 receptor.
- Direct Reverse Transcriptase Inhibition: A drug that directly blocks reverse transcriptase.
- DNA Integrase Inhibition: Inhibition of DNA integrase is a mechanism of action of some drugs.
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Description
Explore the various mechanisms of drug action including enzymatic inhibition, RNA polymerase inhibition, and translational alteration. Additionally, examine the adverse effects associated with these drugs, such as visual disturbances and uric acid elevation. This quiz will enhance your understanding of pharmacological principles.
