Pharmacology Chapter 40: Androgens and Anabolic Steroids
37 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary location of testosterone production in men?

  • Leydig cells in the testicles (correct)
  • Hypothalamus
  • Adrenal glands
  • Pituitary gland

What is the typical estradiol level in a 18-year-old woman?

  • 7-40 pg/mL
  • 17-200 pg/mL (correct)
  • 5-20 ng/mL
  • 10-60 pg/mL

What is the role of androgens in the body?

  • Regulation of ovulation
  • Steroid hormones that promote male characteristics (correct)
  • Development of female secondary sex characteristics
  • Production of estrogen

What is the mechanism of action of androgens?

<p>Stimulation of protein synthesis (A)</p> Signup and view all the answers

What is the typical progesterone level in a pregnant woman during the first trimester?

<p>11.2-90.0 ng/mL (D)</p> Signup and view all the answers

What is the main difference in steroid hormone levels between men and women?

<p>Men have higher levels of testosterone (A)</p> Signup and view all the answers

What is the precursor molecule for steroid hormones?

<p>Cholesterol (C)</p> Signup and view all the answers

What is believed to be a mediator of androgen actions on adipose tissue?

<p>AR actions in muscle (D)</p> Signup and view all the answers

What is a psychological benefit of testosterone?

<p>Improves spatial memory (B)</p> Signup and view all the answers

What is a potential benefit of exercise therapy?

<p>Maintains androgen levels (C)</p> Signup and view all the answers

What is a secondary sex feature promoted by testosterone?

<p>Development of male secondary sex features (D)</p> Signup and view all the answers

What is a cellular benefit of testosterone?

<p>Promotes cellular DNA repair capacity (C)</p> Signup and view all the answers

What is a potential consequence of low testosterone levels?

<p>Depression (C)</p> Signup and view all the answers

What is a physiological benefit of testosterone?

<p>Promotes hematopoiesis (D)</p> Signup and view all the answers

What is the primary function of the hypothalamus in vertebrates, including humans?

<p>To control the reproductive function (A)</p> Signup and view all the answers

How many amino acids does GnRH, the principal molecule that regulates reproductive function, consist of?

<p>10 amino acids (A)</p> Signup and view all the answers

What is the approximate number of neurons that synthesize GnRH in the human hypothalamus?

<p>1000 neurons (C)</p> Signup and view all the answers

What is the name of the hormone that regulates the reproductive function in vertebrates, including humans?

<p>Hypothalamic gonadotropin-releasing hormone (GnRH) (B)</p> Signup and view all the answers

Which of the following is NOT a component of the hypothalamic-pituitary-gonadal (HPG) axis?

<p>Adrenal cortex (C)</p> Signup and view all the answers

What is the title of the journal where the article 'A Population-Level Decline in Serum Testosterone Levels in American Men' was published?

<p>Journal of Clinical Endocrinology and Metabolism (B)</p> Signup and view all the answers

Who is the author of the article 'Hypothalamic-Pituitary-Gonadal (HPG) Axis' published in PNAS in 2007?

<p>J. Larry Jameson (A)</p> Signup and view all the answers

What is the primary cause of erythrocytosis in individuals using anabolic steroids?

<p>Increased red blood cell production (D)</p> Signup and view all the answers

What is the purpose of using anabolic steroids with low androgenic properties?

<p>To minimize unwanted androgenic effects in female patients (A)</p> Signup and view all the answers

Which of the following is a permanent androgenic effect of testosterone?

<p>Deepening of voice (C)</p> Signup and view all the answers

What is the primary cause of testosterone withdrawal?

<p>Testosterone deficiency due to treatment cessation or improper dosing (B)</p> Signup and view all the answers

What is the anabolic-to-androgenic ratio of Winstrol (Stanazolol)?

<p>30:1 (C)</p> Signup and view all the answers

What is the treatment indication of Oxandrin (Oxandrolone)?

<p>Treatment of burn and trauma patients (B)</p> Signup and view all the answers

What is a common side effect of Winstrol (Stanazolol)?

<p>Low E2 (B)</p> Signup and view all the answers

What is the primary reason why total testosterone level may be normal despite excess androgen in certain individuals?

<p>Insulin resistance and hyperinsulinemia (B)</p> Signup and view all the answers

What is the term used to describe hirsutism that develops without excess androgen?

<p>Idiopathic hirsutism (B)</p> Signup and view all the answers

What is the name of the score used to assess the degree of hirsutism?

<p>Ferriman-Gallwey score (B)</p> Signup and view all the answers

What is the potential side effect of using flutamide?

<p>Hepatotoxicity (C)</p> Signup and view all the answers

In individuals with hypothyroidism, what is typically observed?

<p>Low levels of sex hormone–binding globulin (A)</p> Signup and view all the answers

What is the term used to describe the fraction of plasma testosterone that is free or bound to albumin?

<p>Bioavailable testosterone (A)</p> Signup and view all the answers

What is the purpose of using a GnRH analog in combination with an androgen receptor antagonist?

<p>To treat metastatic prostate cancer (B)</p> Signup and view all the answers

What is the name of the androgen receptor antagonist mentioned in the text?

<p>Flutamide (B)</p> Signup and view all the answers

What is the term used to describe the condition where hirsutism develops without excess androgen?

<p>Idiopathic hirsutism (B)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser