Pharmacology: Antihypertensive Agents

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10 Questions

What is a potential adverse effect of using the described drug class during pregnancy?

Hypotension

Which adverse effect is less common with the described drug class compared to ACE inhibitors?

Cough

What is a similarity between the adverse effects of the described drug class and ACE inhibitors?

Risk of angioedema

What is the mechanism of action of diuretics in managing hypertension?

Block the Na/Cl transporter in the distal convoluted tubule

How do sympathoplegics contribute to managing hypertension?

Reducing central sympathetic outflow

Why are combinations of two or more antihypertensive drugs often used for treatment?

Because the drugs act differently

Which of the following statements about ACE Inhibitors is FALSE?

They increase the synthesis of angiotensin II

What is the main therapeutic use of ACE Inhibitors?

Controlling hypertension

Which of the following is a unique pharmacologic property of Angiotensin Receptor Blockers (ARBs) compared to ACE Inhibitors?

They inhibit bradykinin metabolism

Which drug class does Losartan belong to?

Angiotensin Receptor Blockers (ARBs)

This quiz covers the beneficial effects, precautions, and toxicity of antihypertensive agents, specifically in patients with heart failure and chronic renal disease. It also discusses the adverse effects similar to ACE inhibitors, with a focus on the risks during pregnancy. References include lecture notes and a pharmacology textbook.

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