Pharmacology: Antihypertension Drugs

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6 Questions

What is the primary cause of hypertension?

Increased peripheral vascular arteriolar smooth muscle tone

What percentage of patients with hypertension have an unknown cause?

90%

What is a risk factor for hypertension?

Stress

What is a complication of hypertension?

Chronic kidney disease

What is a predisposing factor for hypertension?

High intake of sodium

What is the term for hypertension with no known cause?

Essential hypertension

Study Notes

Hypertension (HTN)

  • HTN results from increased peripheral vascular arteriolar smooth muscle tone, leading to increased arteriolar resistance and reduced capacitance of the venous system.
  • The cause of elevated vascular tone is unknown.

Risk Factors and Complications of HTN

  • HTN is a risk factor for:
    • Chronic kidney disease
    • Myocardial infarction (MI)
    • Heart failure
    • Stroke
    • Blindness

Etiology of HTN

  • Essential HTN: accounts for 90% of patients with unknown cause.
  • Predisposing factors for HTN:
    • Diabetes
    • Obesity
    • Stressful lifestyle
    • High intake of sodium
    • Smoking
    • Race
    • Family history

Classification of Blood Pressure

  • Normal blood pressure categories:
    • Systolic (mm Hg)
    • Diastolic (mm Hg)

Learn about the pharmacology of antihypertension drugs, including their effects on peripheral vascular arteriolar smooth muscle tone and blood pressure.

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