Pharmacology: Antibiotics and Infections
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Questions and Answers

Which of the following antibiotics is known as E-mycin?

  • Clarithromycin
  • Erythromycin (correct)
  • Tetracycline
  • Doxycycline
  • Which antibiotic is not a type of Quinolone?

  • Gentamicin (correct)
  • Ciprofloxacin
  • Moxifloxacin
  • Levofloxacin
  • What is the brand name of the antibiotic Fidaxomicin?

  • E.E.S
  • Zithromax
  • Dificid (correct)
  • Biaxin
  • Which antibiotic is not a type of Macrolide?

    <p>Tetracycline</p> Signup and view all the answers

    Which of the following antibiotics is a type of Tetracycline?

    <p>Minocycline</p> Signup and view all the answers

    Which antibiotic is not a type of Aminoglycoside?

    <p>Metronidazole</p> Signup and view all the answers

    What is the primary difference between community-associated infections and health care–associated infections?

    <p>Source of infection</p> Signup and view all the answers

    Which of the following beta-lactam antibiotics is a penicillinase-resistant drug?

    <p>Oxacillin</p> Signup and view all the answers

    What is the main indication for sulfonamides?

    <p>Urinary tract infections</p> Signup and view all the answers

    Which of the following cephalosporins is a third-generation antibiotic?

    <p>Cefotaxime</p> Signup and view all the answers

    What is the primary use of carbapenems?

    <p>Treatment of severe infections, including intra-abdominal and urinary tract infections</p> Signup and view all the answers

    What is the name of the antibiotic combination that includes imipenem and cilastatin?

    <p>Primaxin</p> Signup and view all the answers

    Study Notes

    Infections

    • Community-associated infections vs Health care–associated infections: two types of infections that occur in different settings.

    Antibiotic Therapy

    • Can lead to Superinfection, Allergic reactions, and severe reactions.

    Sulfonamides

    • Indications: used to treat various infections.
    • Adverse Effects: include allergic reactions, nausea, and vomiting.

    Beta-Lactam Antibiotics

    Natural Penicillins

    • Penicillin G: used to treat streptococcal infections.
    • Penicillin V: used to treat mild to moderate infections.

    Penicillinase-resistant drugs

    • Nafcillin: used to treat methicillin-susceptible Staphylococcus aureus infections.
    • Cloxacillin: used to treat skin and soft tissue infections.
    • Oxacillin: used to treat staphylococcal infections.
    • Dicloxacillin: used to treat skin and soft tissue infections.

    Aminopenicillins

    • Amoxicillin: used to treat bacterial infections such as pneumonia and bronchitis.
    • Ampicillin: used to treat bacterial infections such as meningitis and sepsis.

    Extended-spectrum drugs

    • Carbenicillin: used to treat Pseudomonas aeruginosa infections.
    • Piperacillin: used to treat severe infections such as sepsis and pneumonia.
    • Ticarcillin: used to treat Pseudomonas aeruginosa infections.

    Penicillins

    • Contraindications: allergic reactions, viral infections, and mild infections.
    • Adverse Effects: allergic reactions, diarrhea, and nausea.
    • Interactions: can interact with medications such as warfarin and probenecid.
    • Patient education: inform patients about the importance of completing the full treatment course.

    Cephalosporins

    • Can be grouped into different generations, with each generation having a broader spectrum of activity.
    • Patient education: inform patients about the importance of reporting any allergic reactions.

    Carbapenems

    • Imipenem/cilastatin (Primaxin): used to treat severe infections such as sepsis and pneumonia.
    • Meropenem (Merrem): used to treat severe infections such as meningitis and sepsis.
    • Ertapenem (Invanz): used to treat bacterial infections such as pneumonia and bronchitis.
    • Doripenem (Doribax): used to treat bacterial infections such as pneumonia and urinary tract infections.

    Macrolides

    • Erythromycin (E-mycin, E.E.S, others): used to treat bacterial infections such as pneumonia and bronchitis.
    • Azithromycin (Zithromax): used to treat bacterial infections such as pneumonia and bronchitis.
    • Clarithromycin (Biaxin): used to treat bacterial infections such as pneumonia and bronchitis.
    • Fidaxomicin (Dificid): used to treat Clostridioides difficile infections.
    • Indications: used to treat bacterial infections such as pneumonia and bronchitis.
    • Interactions: can interact with medications such as warfarin and digoxin.
    • Adverse Effects: include nausea, vomiting, and abdominal pain.

    Tetracyclines

    • Demeclocycline (Declomycin): used to treat bacterial infections such as pneumonia and bronchitis.
    • Oxytetracycline (Terramycin): used to treat bacterial infections such as pneumonia and bronchitis.
    • Tetracycline: used to treat bacterial infections such as pneumonia and bronchitis.
    • Doxycycline (Doryx, Vibramycin): used to treat bacterial infections such as pneumonia and bronchitis.
    • Minocycline (Minocin): used to treat bacterial infections such as acne and rosacea.
    • Tigecycline (Tygacil): used to treat bacterial infections such as pneumonia and skin infections.
    • Patient education: inform patients about the importance of taking the medication with water and avoiding milk products.
    • Interactions: can interact with medications such as warfarin and digoxin.
    • Adverse Effects: include nausea, vomiting, and diarrhea.

    Aminoglycosides

    • Gentamicin: used to treat bacterial infections such as pneumonia and meningitis.
    • Neomycin (Neo-Fradin): used to treat bacterial infections such as skin and soft tissue infections.
    • Tobramycin (TOBI): used to treat bacterial infections such as pneumonia and cystic fibrosis.
    • Amikacin: used to treat bacterial infections such as pneumonia and meningitis.
    • Adverse Effects: include ototoxicity and nephrotoxicity.

    Quinolones

    • Ciprofloxacin (Cipro): used to treat bacterial infections such as pneumonia and urinary tract infections.
    • Norfloxacin (Noroxin): used to treat bacterial infections such as urinary tract infections.
    • Levofloxacin (Levaquin): used to treat bacterial infections such as pneumonia and bronchitis.
    • Moxifloxacin (Avelox): used to treat bacterial infections such as pneumonia and bronchitis.
    • Gemifloxacin (Factive): used to treat bacterial infections such as pneumonia and bronchitis.
    • Delafloxacin (Baxdela): used to treat bacterial infections such as pneumonia and skin infections.
    • Indications: used to treat bacterial infections such as pneumonia and urinary tract infections.
    • Interactions: can interact with medications such as warfarin and digoxin.
    • Adverse Effects: include nausea, vomiting, and diarrhea.

    Miscellaneous Antibiotics

    • Metronidazole (Flagyl): used to treat parasitic infections such as giardiasis and amoebiasis.
    • Nitrofurantoin (Macrodantin): used to treat urinary tract infections.
    • Vancomycin: used to treat bacterial infections such as pneumonia and skin infections.
    • Indications: used to treat bacterial infections such as pneumonia and skin infections.

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    Description

    Learn about different types of infections, antibiotic therapy, and various classes of antibiotics, including sulfonamides, beta-lactam antibiotics, and their indications and adverse effects.

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