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Questions and Answers
What are the two main processes of transfer of drugs across cell barriers?
What are the two main processes of transfer of drugs across cell barriers?
- Lipid diffusion and aqueous diffusion (correct)
- Active transport and facilitated diffusion
- Osmosis and filtration
- Endocytosis and exocytosis
Which of the following is a main feature of lipid diffusion of drugs across membranes?
Which of the following is a main feature of lipid diffusion of drugs across membranes?
- Occurs against a concentration gradient
- Involves the use of carrier proteins
- Requires energy in the form of ATP
- Dependent on the lipid solubility of the drug (correct)
What is the main feature of aqueous diffusion of drugs across membranes?
What is the main feature of aqueous diffusion of drugs across membranes?
- Involves binding to specific receptors
- Requires the presence of carrier proteins
- Dependent on the lipid solubility of the drug
- Occurs through water-filled channels or pores (correct)
Which of the following is a specific pharmacokinetic process?
Which of the following is a specific pharmacokinetic process?
What are the three main areas for discussion in the lecture on pharmacokinetics?
What are the three main areas for discussion in the lecture on pharmacokinetics?
Flashcards
Lipid Diffusion
Lipid Diffusion
Movement of drugs across biological membranes via dissolving in lipids.
Aqueous Diffusion
Aqueous Diffusion
Movement of drugs through water-filled channels/pores in cell membranes.
Drug Absorption
Drug Absorption
Movement of a drug from the site of administration to the systemic circulation.
Drug Distribution
Drug Distribution
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Pharmacokinetics main areas
Pharmacokinetics main areas
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Study Notes
Pharmacokinetics Processes
- Two main processes of transfer of drugs across cell barriers are lipid diffusion and aqueous diffusion
- Lipid diffusion is characterized by the ability of drugs to dissolve in and pass through the lipid bilayer of the cell membrane
- Aqueous diffusion involves the movement of drugs through aqueous pores or channels in the cell membrane
Pharmacokinetic Processes
- A specific pharmacokinetic process is the transfer of drugs across cell barriers
- The three main areas for discussion in the lecture on pharmacokinetics are not specified, but typical areas of discussion in pharmacokinetics include absorption, distribution, metabolism, and excretion (ADME) of drugs.
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