24 Questions
What is the process of the body chemically changing a drug into a form that can be excreted?
Drug metabolism
What type of compound is metabolized in the body to produce a drug, and is used to improve drug delivery, decrease toxicity, or target specific cells or tissues?
Prodrug
What is the period of time required for the concentration or amount of a drug in the body to be reduced by one-half?
Half-life (t½)
What is defined as the amount of drug administered being equal to the amount of drug eliminated?
Steady state
Which term refers to the time it takes for a drug to reach minimum effective concentration?
Onset time
What is the highest concentration of a drug in the blood called?
Peak concentration
Which term refers to the length of time taken for a drug to exert a therapeutic effect?
Duration of action
What do you call the highest concentration of a drug in the blood during therapeutic monitoring?
Peak drug level
Which drugs bind to receptors, activate them, and produce a desired response?
'Agonists'
'Nonspecific drugs' affect multiple ____________ sites.
'Receptor'
Epinephrine affects three different receptors: alpha1, beta1, and beta2. These are examples of ________ receptors.
Selective
Which type of drug interaction is characterized by one drug reducing or blocking the effect of another drug?
Antagonistic interaction
What is the process that involves drug movement from the gastrointestinal (GI) tract to the liver?
First pass effect
Which factor can influence drug distribution in the body?
Blood flow
What is the process of drug crossing the blood-brain barrier known as?
Vascular permeability
Which term refers to the ability of a drug to bind to tissue and plasma proteins?
Drugs lipid solubility
What factors can affect drug absorption?
Fasting and food texture
Which process involves the initial metabolism of a drug as it travels from the gastrointestinal tract to the liver?
First pass effect
What method of absorption involves the movement of substances across cell membranes without the use of energy?
Passive transport
What can influence drug distribution in the body?
Tissue perfusion and ability of drug to bind tissue and plasma proteins
Which factor can affect drug absorption?
Food texture and fat content
What influences drug movement across the blood-brain barrier?
Vascular permeability and permeability of cell membranes
What is the term for a drug's ability to bind to tissue and plasma proteins?
Drugs lipid solubility
How can factors like fasting and food texture affect drug absorption?
By impacting disintegration and dissolution processes
Test your knowledge of drug absorption and factors affecting it with this pharmacokinetics quiz. Explore concepts such as disintegration, dissolution, passive transport, diffusion, facilitated diffusion, active transport, and factors influencing absorption.
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