10 Questions
Which process is primarily responsible for the breakdown of proteins?
Proteolysis
What is the primary organ responsible for the catabolism of small proteins?
Kidney
Proteins must generally be smaller than which molecular weight to undergo glomerular filtration?
69 kDa
What concentration comparison is made between lymph and blood for certain proteins?
Lymph concentrations may be higher
Why might targeting the lymphatics be beneficial for certain proteins?
They act on the immune system
Which pathways are utilized for the metabolism of peptide and protein drugs?
Catabolic pathways
What is the molecular weight threshold for proteins that undergo the most efficient glomerular filtration?
30 kDa
What is the fate of proteins after proteolysis?
Broken down into amino acids
Why are proteolytic enzymes significant in the context of protein catabolism?
They are widespread throughout the body and nature
What size must proteins be to have the most effective renal excretion?
Smaller than 30 kDa
This quiz covers the study of pharmacokinetics and pharmacodynamics in pharmaceutical biotechnology, including the processes of absorption, distribution, metabolism, and excretion of peptide and protein drugs.
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