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Questions and Answers
What is the definition of pharmacodynamics of antibacterial drugs?
What is the definition of pharmacodynamics of antibacterial drugs?
- The study of drug absorption, distribution, metabolism, and excretion
- The factors affecting the effectiveness of antibacterial drugs
- The relationship between drug concentration and its antimicrobial effect (correct)
- The principle and parameters of antibacterial drugs
Why is knowledge of a drug's antimicrobial pharmacodynamic effects important?
Why is knowledge of a drug's antimicrobial pharmacodynamic effects important?
- To understand the time course of drug absorption, distribution, metabolism, and excretion
- To determine the dosing interval based on minimal inhibitory concentrations (MICs)
- To define the pharmacokinetics of antibacterial drugs
- To provide a rational basis for determination of optimal dosing regimens (correct)
What does pharmacokinetics refer to?
What does pharmacokinetics refer to?
- The principle and parameters of antibacterial drugs
- The relationship between drug concentration and its antimicrobial effect
- The study of the time course of drug absorption, distribution, metabolism, and excretion (correct)
- The factors affecting the effectiveness of antibacterial drugs
What is the primary focus of pharmacodynamics of antibacterial drugs?
What is the primary focus of pharmacodynamics of antibacterial drugs?
Which aspect provides a more rational basis for determination of optimal dosing regimens for antibacterial drugs?
Which aspect provides a more rational basis for determination of optimal dosing regimens for antibacterial drugs?
What does the pharmacodynamics of an antimicrobial drug entail?
What does the pharmacodynamics of an antimicrobial drug entail?
What is the main principle pharmacodynamic parameter used to assess the antimicrobial activity of drugs?
What is the main principle pharmacodynamic parameter used to assess the antimicrobial activity of drugs?
What must the antibiotic concentration at the site of infection exceed in order to obtain an antimicrobial effect?
What must the antibiotic concentration at the site of infection exceed in order to obtain an antimicrobial effect?
What describes the minimal concentration of antibiotic that prevents a clear suspension of 105 colony-forming units (CFUs) of bacteria/mL from becoming turbid?
What describes the minimal concentration of antibiotic that prevents a clear suspension of 105 colony-forming units (CFUs) of bacteria/mL from becoming turbid?
What is responsible for therapeutic success in the relationship between pharmacodynamics and pharmacokinetics of antimicrobial drugs?
What is responsible for therapeutic success in the relationship between pharmacodynamics and pharmacokinetics of antimicrobial drugs?
Which parameter is used to assess the in vitro antimicrobial activity of drugs, usually determined by finding the MIC and MBC?
Which parameter is used to assess the in vitro antimicrobial activity of drugs, usually determined by finding the MIC and MBC?
What is necessary for bacteriostatic drugs to clear tissues of infecting microorganisms?
What is necessary for bacteriostatic drugs to clear tissues of infecting microorganisms?
Which type of antibacterial drugs primarily require host defences to clear tissues of infecting microorganisms?
Which type of antibacterial drugs primarily require host defences to clear tissues of infecting microorganisms?
What describes when antibacterial action continues for a period after antibiotic level falls below its MIC?
What describes when antibacterial action continues for a period after antibiotic level falls below its MIC?
