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Questions and Answers
Which mechanism(s) does drug absorption occur through?
Which mechanism(s) does drug absorption occur through?
- None of the above
- Specialized transport mechanisms only
- Both passive diffusion and specialized transport mechanisms (correct)
- Passive diffusion only
What affects dissolution rate and solubility of a drug?
What affects dissolution rate and solubility of a drug?
- Crystal or amorphous drug form only
- Salt forms only
- Both particle size and crystal or amorphous drug form and salt forms (correct)
- Particle size only
What do bioavailability and bioequivalence describe?
What do bioavailability and bioequivalence describe?
- Both the rate and extent of drug absorption (correct)
- None of the above
- The extent of drug absorption only
- The rate of drug absorption only
What must generic drugs be compared to?
What must generic drugs be compared to?
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Which of the following is NOT a route of drug administration?
Which of the following is NOT a route of drug administration?
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What is drug metabolism or biotransformation?
What is drug metabolism or biotransformation?
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How are drugs excreted from the body?
How are drugs excreted from the body?
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What are some pharmacokinetic principles?
What are some pharmacokinetic principles?
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How can dosage regimen considerations be approached?
How can dosage regimen considerations be approached?
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Which of the following does NOT affect solubility and dissolution of a drug?
Which of the following does NOT affect solubility and dissolution of a drug?
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Study Notes
- Drug absorption occurs through passive diffusion or specialized transport mechanisms.
- Particle size affects dissolution rate and solubility.
- Crystal or amorphous drug form and salt forms affect solubility and dissolution.
- Bioavailability and bioequivalence describe the rate and extent of drug absorption.
- Generic drugs must be bioequivalent to their brand-name counterparts.
- Different routes of drug administration include oral, rectal, parenteral, epicutaneous, ocular, otic, nasal, and others.
- Drug metabolism or biotransformation involves chemical changes to drugs within the body.
- Excretion of drugs occurs through various bodily fluids.
- Pharmacokinetic principles include half-life, clearance, and dosage regimen considerations.
- Dosage regimen considerations can be approached empirically or kinetically.
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