Podcast
Questions and Answers
Which type of inhibition is characterized by drug binding to the enzyme site only after the substrate binds?
Which type of inhibition is characterized by drug binding to the enzyme site only after the substrate binds?
- Uncompetitive inhibition (correct)
- Irreversible inhibition
- Non-competitive inhibition
- Competitive inhibition
Which enzyme target is associated with the clinical use of ACE inhibitors like captopril?
Which enzyme target is associated with the clinical use of ACE inhibitors like captopril?
- HMG-CoA reductase
- Thyroid peroxidase
- Angiotensin converting enzyme (correct)
- Cycloxygenase enzymes
Which transporter family utilizes energy derived from downhill movement of a solute to transport molecules in secondary active transport?
Which transporter family utilizes energy derived from downhill movement of a solute to transport molecules in secondary active transport?
- Solute-carrier (SLC) family (correct)
- Membrane pumps
- ATP-Binding Cassette (ABC) superfamily
- Membrane channels
Which transporter, also known as MDR1 transporter, affects the pharmacokinetics of drugs by affecting entry and exit from selective tissues?
Which transporter, also known as MDR1 transporter, affects the pharmacokinetics of drugs by affecting entry and exit from selective tissues?
Which type of secondary active transporters use the flow of one molecule/ion to move another in the opposite direction?
Which type of secondary active transporters use the flow of one molecule/ion to move another in the opposite direction?
Which type of ion channels open and close depending on transmembrane potentials?
Which type of ion channels open and close depending on transmembrane potentials?
Which drug is classified as a calcium channel blocker?
Which drug is classified as a calcium channel blocker?
Which type of enzyme inhibition is characterized by the drug binding to the allosteric site?
Which type of enzyme inhibition is characterized by the drug binding to the allosteric site?
What effect can be observed by increasing the substrate concentration in competitive enzyme inhibition?
What effect can be observed by increasing the substrate concentration in competitive enzyme inhibition?
Which drug is classified as a sodium channel blocker used as a local anesthetic?
Which drug is classified as a sodium channel blocker used as a local anesthetic?
Which type of inhibition is characterized by the drug binding to the allosteric site?
Which type of inhibition is characterized by the drug binding to the allosteric site?
Which drug is classified as a potassium channel blocker used for antiarrhythmic purposes?
Which drug is classified as a potassium channel blocker used for antiarrhythmic purposes?
Which type of ion channels open and close depending on transmembrane potentials?
Which type of ion channels open and close depending on transmembrane potentials?
Which enzyme inhibition type is characterized by the effects of the inhibitor being reduced by increasing substrate concentration?
Which enzyme inhibition type is characterized by the effects of the inhibitor being reduced by increasing substrate concentration?
Which drug is classified as a calcium channel blocker used as an antihypertensive?
Which drug is classified as a calcium channel blocker used as an antihypertensive?
Which of the following statements best characterizes uncompetitive inhibition?
Which of the following statements best characterizes uncompetitive inhibition?
Which enzyme target is associated with the clinical use of HMG-CoA reductase inhibitors like atorvastatin and rosuvastatin?
Which enzyme target is associated with the clinical use of HMG-CoA reductase inhibitors like atorvastatin and rosuvastatin?
Which transporter family utilizes energy from ATP hydrolysis to actively move ions or drug molecules against their electrochemical gradient?
Which transporter family utilizes energy from ATP hydrolysis to actively move ions or drug molecules against their electrochemical gradient?
Which type of transporters use the natural flow of one molecule/ion to move another in the same direction against its electrochemical gradient?
Which type of transporters use the natural flow of one molecule/ion to move another in the same direction against its electrochemical gradient?
Which type of enzyme inhibition is characterized by drug binding to the enzyme site only after the substrate binds, with minimal displacement and decreased Vmax?
Which type of enzyme inhibition is characterized by drug binding to the enzyme site only after the substrate binds, with minimal displacement and decreased Vmax?
