Pharmaceuticals Tablet Compression Mechanisms

Modification of crystalline solid ______ or chemically to produce a particle with the desired properties.

We can also modify the ______ by changing the surface of the particles or the particle size.

This can have an influence when we change the crystalline properties we can have an influence on the ______ compaction and the mechanical behavior of the material.

The importance of having a ______ property to allow the permanent deformation during compression.

Powder properties as well in terms of ______ and mixing and dry powder inhalation systems.

The ______ size, this is an influential factor during the tableting process.

The irreversible deformation is the ______ deformation when the bone will snap and the molecular change location into a different position.

The ______ properties are affected during the tableting process, such as the deformation and pressure.

The ______ shape as well is another important determinant during the tableting process, and these powder particles can be present in different shapes.

The pressure applied during the tableting process is known as the ______ pressure.

Tablet properties such as ______ and dissolution can be influenced by the excipients we add in the formulation.

The learning objectives include explaining the influence of ______ on tabletting process.

The more you know about your ______, the better flexibility you will have during formulation.

Tablets are generally manufactured from a blend of ______, different materials, they have different properties.

The ______ of the material properties on making tablets in addition to improve tabletting process by manipulating material properties.

While compressing a mass of powder, we make a ______ so it’s a loose lump of powder changed into a compact mass.

If the material is going to be ______, it will bounce back and cause problems later during the tableting process.

The ______ behavior of the material allows us to reshape it during the compression process.

When we fill the dye with granules and start to apply the ______, the particles will start to move, become closer to each other.

Increased tablet strength is associated with ______ original particle size.

The ______ of the material will resist until it reaches the yield point, and then it will snap.

Changes in ______ during the compaction process can affect the relationship between particle size and tablet strength.

Measuring the change in ______ before and after compaction can help assess the effects of compression on tablet surface area.

The plot shows the change in ______ with increased pressure during compression for three materials.

The surface area of a particulate solid can be measured using techniques such as ______ adsorption or mercury intrusion.

When you compress a mass of powder in a tablating machine, the particles will start to come closer to each other and lead to ______ of the gaps and void spaces.

As the load keeps increasing, the particles will keep coming together until there will be no further ______ and the particles are sitting very close to each other.

The sequence of events will start with increasing the ______ on the mass of powder inside the dye.

The particles will be packed together and this will lead to ______ because at the beginning it's a porous lump full of gaps, void spaces.

The process of compressing powder will result in the elimination of ______ spaces and the particles will be sitting very close to each other.

The event properties of a crystalline solid that can be manipulated include the ______, the shape, the internal structure, and the surface of the crystalline material.

So how would you expect the ______ of a tablet to vary with particle size?

So this figure illustrates the relationship between the ______ force and the crystalline diameter.

The higher the ______ strength, the smaller the particles, the lower the ______ strength, the larger the particles.

The pattern for the two materials is the same, but there are differences between the two ______.

Sodium chloride, widely used in the pharmaceutical industry, and ______, which is API used as a unidirectional antiseptic, are two examples of materials used in the study.

Let’s see how this diameter is responding to the ______ force.

The x-axis showing the ______ force to crush these particles.

The y-axis is linked with the change in the ______ diameter.

That’s what we are going to investigate in this part of the ______.

Match the following terms related to material properties with their descriptions:

Match the following methods with their application in particle analysis:

Match the following terms with their effects on tablet strength:

Match the following terms with their applications in tablet manufacturing:

Match the following terms with their roles in the tableting process:

Match the following particle properties with their effects on the tableting process:

Match the following material properties with their effects on tablet strength:

Match the following compaction processes with their effects on the material:

Match the following surface area analysis techniques with their applications:

Match the following material properties with their effects on the tableting process:

Match the following material properties with their influence on tabletting process:

Match the following surface area analysis techniques with their application in pharmaceuticals:

Match the following compaction pressure effects with their consequence on tablet properties:

Match the following material properties with their effect on tabletting process:

Match the following particle size distribution effects with their influence on tabletting process:

Match the following terms with their effects on tablet strength:

Match the following material properties with their influence on tabletting process:

Match the following methods with their application in surface area analysis:

Match the following terms with their effects on particle size distribution:

Match the following terms with their effects on compaction pressure:

Match the following material properties with their effects on tablet strength:

Match the following surface area analysis techniques with their applications in pharmaceuticals:

Match the following particle properties with their effects on the tableting process:

Match the following compaction processes with their effects on the material:

Match the following material properties with their influence on the tableting process:

Match the following material properties with their effects on tablet strength:

Match the following particle properties with their effects on the tableting process:

Match the following surface area analysis techniques with their applications:

Match the following compaction processes with their effects on the material:

Match the following material properties with their effects on tabletting process:

Match the following material properties with their influence on tablet strength:

Match the following surface area analysis techniques with their applications:

Match the following compaction pressure effects with their consequence on tablet properties:

Match the following particle properties with their effects on tablet strength:

Match the following material properties with their effects on tabletting process:

Match the following methods with their application in particle analysis:

Match the following terms with their roles in the tableting process:

Match the following material properties with their influence on tabletting process:

Match the following terms with their descriptions:

Match the following particle size distribution effects with their influence on tabletting process: