Pharmaceutical Materials and Properties

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25 Questions

What is the purpose of the screen in the base of the mill casing?

To retain material in the mill until sufficient size reduction

What happens to the material in the mill until a certain point?

It is retained until a sufficient degree of size reduction

What is a characteristic of the screen in the mill?

It is self-classifying

What is the outcome of the material being retained in the mill?

It undergoes a sufficient degree of size reduction

What is the function of the screen in relation to the material?

To retain the material until a sufficient degree of size reduction

What can heat affect?

Thermolabile materials

What can affect the size of a product?

Heat

What is the effect of heat on thermolabile materials?

Destruction

What is a characteristic of thermolabile materials?

They are sensitive to heat

What type of materials are affected by heat?

Thermolabile materials

What type of pharmaceutical materials have high toughness?

Fibrous drugs

What is a characteristic of fibrous pharmaceutical materials?

High toughness

Which of the following pharmaceutical materials are NOT characterized by high toughness?

Liquid drugs

What is a common property of pharmaceutical materials that are fibrous in nature?

High toughness

Which of the following is a characteristic of many pharmaceutical materials?

High toughness

What is the result of excessive feed?

Cushioning effect

What is the opposite of a cushioning effect?

Size reduction

What occurs when feed is excessive?

Cushioning effect

What is the term for too much feed?

Excessive feed

At what point does maximum size reduction occur?

When feed is sufficient

What type of materials are typically processed using coarse degree of size reduction?

Tough fibrous materials

What is the purpose of coarse degree of size reduction for tough fibrous materials?

To facilitate extraction

Which of the following examples is NOT a type of material that requires coarse degree of size reduction?

Spinach

What is the significance of coarse degree of size reduction in the processing of tough fibrous materials?

It is necessary prior to extraction

What is the characteristic of materials that require coarse degree of size reduction?

They are tough and fibrous

Study Notes

Milling in Pharmaceutical Materials

  • Fibrous drugs, such as roots, peels, and wood, exhibit high toughness.
  • A screen in the mill casing acts as a self-classifying mechanism, retaining material until a sufficient degree of size reduction is achieved.
  • Coarse size reduction is suitable for tough fibrous materials, such as liquorice and rhubarb, prior to extraction.

Factors Affecting Milling

  • Heat can affect thermolabile materials during the milling process.
  • The size of the product can be controlled, with maximum size reduction occurring under optimal conditions.

Milling Limitations

  • Excessive feed can produce a cushioning effect, limiting the milling process.

This quiz covers the properties of pharmaceutical materials, including their toughness and structure, particularly in fibrous drugs.

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