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Pharmaceutical Emulsions and Ointment Formulation

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20 Questions

What is the typical size range of droplets in emulsions?

0.1 – 100 μm

What is the main advantage of using emulsions in oral administration of oils and oil-soluble drugs?

Enhanced palatability

What is the main characteristic of o/w emulsions in terms of miscibility?

Miscible with water

What determines the type of emulsion formed by an emulsifying agent?

Solubility of the emulsifying agent

What is the ideal property of an emulsifying agent in terms of toxicity?

Non-toxic

What is the primary function of tragacanth in emulsions?

To increase viscosity and prevent creaming

Which type of emulsifying agent is suitable for internal preparations due to its non-toxic and non-irritant properties?

Non-ionic emulsifying agent

What is the primary reason for choosing an emulsifying agent?

Based on the active ingredient and use of the product

Which of the following emulsifying agents is suitable for parenteral use?

Polysorbate 80

What is the purpose of flavouring agents in polysorbate emulsions?

To mask the unpleasant taste of the emulsion

What is the primary reason why acacia is not used externally in emulsions?

It is too sticky

What is the purpose of antimicrobial preservatives in emulsions?

To prevent the growth of bacteria in the water phase

What happens when the interfacial film of an emulsion is broken?

Cracking occurs

What is the effect of increasing the chain length of macrogols?

It becomes a liquid with good solvent properties

What is the primary characteristic of vegetable oils used in skin preparations?

They are occlusive

What is the characteristic of silicone oils?

Very hydrophobic and water repellent

What is the composition of hydrous wool fat?

7 parts wool fat and 3 parts water

What is the purpose of surfactants in ointments?

To allow them to be washed off easily

At what temperature are oily components melted in the preparation of creams?

60°C

When are unstable and insoluble drugs added to creams?

By trituration after the mixture has cooled

Learn about the formulation of emulsions and ointments in pharmaceuticals, including the importance of emulsifying agents and the benefits of using emulsions for oral, rectal, and topical administration. Understand how emulsions can enhance palatability and increase absorption of oil and oil-soluble drugs.

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