Pharmaceutical Emulsions and Ointment Formulation

Play an AI-generated podcast conversation about this lesson

What is the typical size range of droplets in emulsions?

0.1 – 100 μm (correct)

1 – 1000 μm

0.01 – 1 μm

10 – 1000 μm

What is the main advantage of using emulsions in oral administration of oils and oil-soluble drugs?

Enhanced palatability (correct)

Reduced absorption

Increased toxicity

Increased dose frequency

What is the main characteristic of o/w emulsions in terms of miscibility?

Miscible with both oil and water

Miscible with oil

Immiscible with both oil and water

Miscible with water (correct)

What determines the type of emulsion formed by an emulsifying agent?

Solubility of the emulsifying agent Signup and view all the answers

What is the ideal property of an emulsifying agent in terms of toxicity?

Non-toxic Signup and view all the answers

What is the primary function of tragacanth in emulsions?

To increase viscosity and prevent creaming Signup and view all the answers

Which type of emulsifying agent is suitable for internal preparations due to its non-toxic and non-irritant properties?

Non-ionic emulsifying agent Signup and view all the answers

What is the primary reason for choosing an emulsifying agent?

Based on the active ingredient and use of the product Signup and view all the answers

Which of the following emulsifying agents is suitable for parenteral use?

Polysorbate 80 Signup and view all the answers

What is the purpose of flavouring agents in polysorbate emulsions?

To mask the unpleasant taste of the emulsion Signup and view all the answers

What is the primary reason why acacia is not used externally in emulsions?

It is too sticky Signup and view all the answers

What is the purpose of antimicrobial preservatives in emulsions?

To prevent the growth of bacteria in the water phase Signup and view all the answers

What happens when the interfacial film of an emulsion is broken?

Cracking occurs Signup and view all the answers

What is the effect of increasing the chain length of macrogols?

It becomes a liquid with good solvent properties Signup and view all the answers

What is the primary characteristic of vegetable oils used in skin preparations?

They are occlusive Signup and view all the answers

What is the characteristic of silicone oils?

Very hydrophobic and water repellent Signup and view all the answers

What is the composition of hydrous wool fat?

7 parts wool fat and 3 parts water Signup and view all the answers

What is the purpose of surfactants in ointments?

To allow them to be washed off easily Signup and view all the answers

At what temperature are oily components melted in the preparation of creams?

60°C Signup and view all the answers

When are unstable and insoluble drugs added to creams?

By trituration after the mixture has cooled Signup and view all the answers