Podcast
Questions and Answers
What is the purpose of applying a poultice topically?
What is the purpose of applying a poultice topically?
- To provide cooling relief
- To inject medication intravenously
- To administer drugs orally
- To provide heat or counter-irritation (correct)
What is the main difference between a pessary and a suppository?
What is the main difference between a pessary and a suppository?
- Pessaries are used for topical application, while suppositories are used for injection
- Pessaries are deposited in the uterus or vagina, while suppositories are inserted rectally (correct)
- Pessaries are used for parental administration, while suppositories are used for inhalation
- Pessaries are used for oral administration, while suppositories are used for topical application
What is the purpose of nebulization in inhalation dosage forms?
What is the purpose of nebulization in inhalation dosage forms?
- To inject medication intravenously
- To break up fluids into micro-particles by ultrasound (correct)
- To provide cooling relief
- To administer drugs in a vapour by means of vaporization and heat
What is the advantage of using topical preparations?
What is the advantage of using topical preparations?
What is the purpose of using transdermal patches?
What is the purpose of using transdermal patches?
What is the main advantage of using inhalation dosage forms?
What is the main advantage of using inhalation dosage forms?
What is the primary characteristic of a cream?
What is the primary characteristic of a cream?
Which type of preparation is used for rectal administration?
Which type of preparation is used for rectal administration?
What is the purpose of a collodion?
What is the purpose of a collodion?
What is the primary difference between an ointment and a paste?
What is the primary difference between an ointment and a paste?
What is a transdermal patch?
What is a transdermal patch?
What is the characteristic of a suppository?
What is the characteristic of a suppository?
What is a major factor that determines the ionization state of a drug?
What is a major factor that determines the ionization state of a drug?
What is the primary goal of the pharmaceutical process in preparing drug formulations?
What is the primary goal of the pharmaceutical process in preparing drug formulations?
What is a characteristic of sustained-release formulations used in veterinary medicine?
What is a characteristic of sustained-release formulations used in veterinary medicine?
What determines the rate at which drug formulations dissolve?
What determines the rate at which drug formulations dissolve?
What is a factor that influences the bioavailability of a drug?
What is a factor that influences the bioavailability of a drug?
What is a characteristic of a drug formulation that determines its absorption rate across the gastric mucosa?
What is a characteristic of a drug formulation that determines its absorption rate across the gastric mucosa?
Study Notes
Dosage Forms
- A poultice is a sticky, moist preparation applied externally to provide heat or counter-irritation.
- A pessary is a solid dosage form deposited in the uterus or vagina, dissolving in fluids present.
Inhalation Dosage Forms
- An aerosol is a drug dosage form administered by inhalation, using a propellant.
- Nebulization is the administration of drugs dispersed as very small droplets of fluid, broken up into micro-particles by ultrasound.
- Vaporisation is the administration of a drug in a vapour form, using heat, e.g. steam.
Routes of Administration of Drugs
- Oral administration includes sub-lingual administration.
- Parenteral administration includes intravenous (IV), intramuscular (IM), subcutaneous (SC), intraperitoneal, intraosseous, and intrathecal routes.
- Topical administration includes ointments, creams, lotions, and transdermal patches.
Topical Preparations
- Ointments are semi-solid, viscous preparations applied to the skin or mucous membranes.
- Enemas are fluid preparations for rectal administration.
- Lotions are watery preparations for external application without friction.
- Creams are semi-solid emulsions that spread easily when applied to the skin.
- Suppositories are solid drug forms for insertion into a body cavity, made of a base that melts at body heat.
- Liniments are solutions of an irritant substance in alcohol, a fixed oil, or a soap, applied to the skin by inunction or rubbing.
- Collodions are solutions of pyroxylin and colophony in alcohol and ether, forming a solid protective film when applied to the skin.
- Transdermal patches are gels with or without a cover, placed on the skin.
Factors Affecting Bioavailability
- Size: Large drug molecules will not pass through membranes.
- pKa: The pKa of the drug determines if it is ionised or unionised.
Pharmaceutical Process
- The manufacturing process can affect physical and chemical characteristics of drug formulations, influencing bioavailability.
- Inert ingredients like carriers, binding agents, and coatings are used to prepare different dosage forms.
- These ingredients affect the rate of dissolution of formulations.
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Description
This quiz covers different types of pharmaceutical dosage forms, including poultices, pessaries, and inhalation methods such as aerosols and nebulization. Understand the characteristics and uses of each dosage form.