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What is the difference between solubility and dissolution?
What is the difference between solubility and dissolution?
- Solubility refers to the maximum amount of a substance that can dissolve in a solvent at a specific temperature, while dissolution is the process by which a solid substance dissolves in a solvent to form a solution. (correct)
- Solubility and dissolution both refer to the maximum amount of a substance that can dissolve in a solvent at a specific temperature.
- Solubility is the process by which a solid substance dissolves in a solvent to form a solution, while dissolution refers to the maximum amount of a substance that can dissolve in a solvent at a specific temperature.
- Solubility and dissolution are synonymous and can be used interchangeably.
What influences the choice of dosage form according to the text?
What influences the choice of dosage form according to the text?
- Manufacturing cost
- Biological interactions
- Color and appearance
- Physico-chemical properties (correct)
What does the text discuss in relation to water and pharmaceuticals?
What does the text discuss in relation to water and pharmaceuticals?
- The role of water in pharmaceutical manufacturing
- The influence of water on pharmaceutical marketing
- The impact of water on pharmaceutical color and appearance
- The critical effects of water on pharmaceuticals (correct)
What is the interplay discussed in the text in relation to the development of a final dosage form?
What is the interplay discussed in the text in relation to the development of a final dosage form?
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What does the text mention in relation to particles and powders?
What does the text mention in relation to particles and powders?
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Study Notes
Solubility vs. Dissolution
- Solubility refers to the maximum amount of a substance that can dissolve in a given amount of solvent at a specific temperature.
- Dissolution is the process of a substance dissolving in a solvent.
Dosage Form Selection
- The choice of dosage form is influenced by factors such as the route of administration, stability, and bioavailability of the drug.
Water and Pharmaceuticals
- Water is a critical component in the pharmaceutical industry, used as a solvent, vehicle, or reactant in various stages of drug development and manufacturing.
Development of Final Dosage Form
- The interplay between solubility, dissolution, and bioavailability is crucial in the development of a final dosage form, as it affects the drug's efficacy and safety.
Particles and Powders
- Particle size and powder properties can significantly impact the dissolution rate and solubility of a drug, making it essential to consider these factors during formulation and manufacturing.
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